AHC Bibliography

View the updated  Bibliography 2014

Updated June 4, 2013

In honor of the twentieth anniversary of the Alternating Hemiplegia of Childhood Foundation, the AHCF is happy to present this bibliography of articles on Alternating Hemiplegia of Childhood and related topics. 

The articles included in this bibliography were selected to help parents locate information on a variety of topics related to this disorder. This is by no means a complete listing of all articles on Alternating Hemiplegia of Childhood. 

If anyone would like to suggest the inclusion of a new citation, or has any comments regarding the bibliography, please forward them to Vicky Platt at Vicky@ahckids.org.

To obtain the full text of these articles you may:

  1. Check the internet to see if a copy of the article is available for free (i.e. Google Scholar)
  2. Go to the publisher’s web site. Some publishers provide free access to an article after you register as a guest; while others require payment.
  3. Some local public libraries have copies of medical journals or can get a copy of an article for you. Ask your local librarian about inter-library loan options and if fees are involved.

MOST RECENT ARTICLES

Di Michele, M, Goubau, C, Waelkens, E, Thys, C, De Vos, R, Overbergh, L, Schyns, T, Buyse, G, Casaer, P, Van Geet, C, Freson, K. “Functional Studies and Proteomics in Platelets and Fibroblasts Reveal a Lysosomal Defect with Increased Cathepsin-dependent Apoptosis in ATP1A3 Defective Alternating Hemiplegia of Childhood.” Journal of Proteomics. May 13, 2013.

Save, J, Poncelin, D, Auvin, S. “Caregiver’s Burden and Psychosocial Issues in Alternating Hemiplegia of Childhood.” Eur J Paediatr Neurol. May 11, 2013. 

Kansagra, S, Mikati, Mohamad, Vigevano, F. “Chapter 85 – Alternating Hemiplegia of Childhood.” Handbook of Clinical Neurology. 2013 May, Vol. 112, Pages 821-826. Winchester, S, Singh, P, Mikati, Mohamad. “Chapter 127 – Ataxia.” Handbook of Clinical Neurology. 2013 May, Vol. 112, Pages 1213-1217.

Kirshenbaum, GS, Dawson, N, Mullins, JG, Johnston, TH, Drinkhill, MJ, Edwards, IJ, Fox SH, Pratt, JA, Brotchie, JM, Roder, JC, Clapcote, SJ. “Alternating Hemiplegia of Childhood-Related Neural and Behavioural Phenotypes in Na+K+-ATPase a3 Missense Mutant Mice.” PLoS One, 2013, Vol. 8 No.3.

Ishi A, Saito, Y, Mitsui, J, and others. “Identification of ATP1A3 Mutations by Exome Sequencing as the Cause of Alternating Hemiplegia of Childhood in Japanese Patients.” PloS one, 2013 Feb., Vol. 8 No. 2.

Aminkeng, F. “Mutations in ATP1A3 Cause Alternating Hemiplegia of Childhood.” Clinical Genetics, Jan 2013, Vol. 83 No.1, Pages 32-3.

Alexoudi, A, Schneider, SA. “Alternating Hemiplegia of Childhood and Rapid-onset Dystonia Parkinsonism are Allelic Disorders due to ATP1A3 Gene Mutations.” Movement Disorders. Oct. 2012, Page 1494.

Traut, M, Cavagnari, B, Mendez, JH, Amartino, H. “Alternating Hemiplegia of Childhood: A Case Report and Literature Review.” Arch Argent Pediatr, Oct. 2012. (In Spanish)

Wagener-Schimmel, L, Nicolai, J. “Child Neurology” Benign Nocturnal Alternating Hemiplegia of Childhood.” Neurology. 2012 Oct, 30. Vol.79 No.18, Pages 161-163.

Chi, L, Zhao, X, Liu, X. “Alternating Hemiplegia of Childhood in Chinese Following Long-Term Treatment with Flunarizine or Topiramate.” The International Journal of Neuroscience. Sept. 2012, Vol. 122 No.9, Pages 506-510.

Heinzen, E, Swoboda, K, Hitomi, Y, and others. “De Novo Mutations in ATP1A3 Cause Alternating Hemiplegia of Childhood.” Nature Genetics, Sept. 2012, Vol. 44, No.9, Pages 1030-1034.

Ozelius, L. “Clinical Spectrum of Disease Associated with ATP1A3 Mutations.” Lancet Neurology. 2012 Sept. Vol. 11 No. 9, Pages 741-743.

Rosewich, H, Thiele, H, Ohlenbusch, A, and others. “Heterozygous De-Novo Mutations in ATP1A3 in Patients with Alternating Hemiplegia of Childhood: A Whole-Exome Sequencing Gene-Identification Study.” Lancet Neurology, 2012 Sep. Vol. 11 No.9, Pages 764-73.

Incorpora, G, Pavone, P, Polizzi, A, and others. “An 11-Year Follow-up Study of Neonatal-Onset, Bath-induced Alternating Hemiplegia of Childhood in Twins.” Journal of Child Neurology. 2012 May, Vol. 27 No. 5, Pages 657-662.

Inui, T, Saito, Y, Sakuma, H, and others. “Profiles of Blood Biomarkers in Alternating Hemiplegia of Childhood—Increased MMP-9 and Decreased Substance P Indicates its Pathophysiology.” Brain & Development. 2012 Mar., Vol. 34 No. 3, Pages 196-200.

Fons, C, Campistol, J, Panagiotakaki, E, and others. “Alternating Hemiplegia of Childhood: Metabolic Studies in the Largest European Series of Patients.” European Journal of Paediatric Neurology. Jan 2012, Vol. 16 No.1, Pages 10-14.

Badoe, EV. “Alternating Hemiplegia in a Child Misdiagnosed as Intractable Epilepsy Successfully Treated with Aripiprazole: A Case Study.” West Afr J Med. Mar-Apr 2011 Pages 140-144.

DYSTONIA

Andermann F, Ohtahara S, Andermann E, Camfield P, Kobayashi K. “Infantile Hypotonia and Paroxysmal Dystonia: A Variant of Alternating Hemiplegia of Childhood.” Movement Disorders, 1994 Mar, Vol.9 No.2, Pages 227-229.

EPILEPSY

Aicardi J. “Alternating Hemiplegia of Childhood.” Chapter 24 Epilepsy and Movement Disorders. Renzo G, Andermann F, Hallett M. Cambridge University Press 2002, Pages 379-392.

Badoe, EV. “Alternating Hemiplegia in a Child Misdiagnosed as Intractable Epilepsy Successfully Treated with Aripiprazole: A Case Study.” West Afr J Med. Mar-Apr 2011, Pages 140-144.

Shirasaka Y, Ito M, Okuno T, Mikawa H, Yamori Y. “Epileptic Seizures Difficult to Differentiate from Alternating Hemiplegia in Infants: A Case Report.” Brain Development. 1990, Vol.12 No.5, Pages 521-524.

GENETICS

Alexoudi, A, Schneider, SA. “Alternating Hemiplegia of Childhood and Rapid-onset Dystonia Parkinsonism are Allelic Disorders due to ATP1A3 Gene Mutations.” Movement Disorders. Oct. 2012, Page 1494.

Bassi MT, Bresolin N, Tonelli A. “A Novel Mutation in the ATP1A2 Gene Causes Alternating Hemiplegia of Childhood.” Journal of Medical Genetics, 2004, Vol.41 Pages 621-628.

Boileau S, Vuillaume I, Sablonniere B, Marignier S, Des Portes V, Vallee L, Auvin S. “Absence of T378N Mutation of ATP1A2 Gene in Five Patients with Alternating Hemiplegia of Childhood.” Developmental Medicine and Child Neurology, 2008 Nov., Vol.50 No.11, Pages 879-880.

Di Michele, M, Goubau, C, Waelkens, E, Thys, C, De Vos, R, Overbergh, L, Schyns, T, Buyse, G, Casaer, P, Van Geet, C, Freson, K. “Functional Studies and Proteomics in Platelets and Fibroblasts Reveal a Lysosomal Defect with Increased Cathepsin-dependent Apoptosis in ATP1A3 Defective Alternating Hemiplegia of Childhood.” Journal of Proteomics. May 13, 2013.

De Vries, B, Haan, J, Stam, AH, Vanmolkot, KR, Stoink, H, Laan, LA, Gill, DS, Pascual, J, Frants, RR, van den Maagdenberg, AM, Ferrari, MD. “Alternating Hemiplegia of Childhood: No Mutations in the Glutamate Transporter EAAT1.” Neuropediatrics. Oct 2006, Pages 302- 304.

Heinzen, E, Swoboda, K, Hitomi, Y, and others. “De Novo Mutations in ATP1A3 Cause Alternating Hemiplegia of Childhood.” Nature Genetics, Sept. 2012, Vol. 44, No.9, Pages 1030-1034.

Inui, T, Saito, Y, Sakuma, H, and others. “Profiles of Blood Biomarkers in Alternating Hemiplegia of Childhood—Increased MMP-9 and Decreased Substance P Indicates its Pathophysiology.” Brain & Development. 2012, Mar., Vol. 34 No. 3, Pages 196-200.

Ishi A, Saito, Y, Mitsui, J, and others. “Identification of ATP1A3 Mutations by Exome Sequencing as the Cause of Alternating Hemiplegia of Childhood in Japanese Patients.” PloS one, 2013 Feb., Vol. 8 No. 2.

Jen JC, Wan J, Palos TP, Howard BD, Baloh RW. “Mutation in the Glutamate Transporter EAAT1 Causes Episodic Ataxia, Hemiplegia, and Seizures.” Neurology, 2005 Aug 23, Vol.65 No.4, Pages 529-534.

Kanavakis E, Xaidara A, Papathanasiou-Klontza D, Papadimitriou A, Velentza S, Youroukos S. “Alternating Hemiplegia of Childhood: A Syndrome Inherited with an Autosomal Dominant Trait.” Developmental Medicine and Child Neurology, 2003 Dec., Vol.45 No.12, Pages 833-836

Kirshenbaum, GS, Dawson, N, Mullins, JG, Johnston, TH, Drinkhill, MJ, Edwards, IJ, Fox SH, Pratt, JA, Brotchie, JM, Roder, JC, Clapcote, SJ. “Alternating Hemiplegia of Childhood-Related Neural and Behavioural Phenotypes in Na+K+-ATPase a3 Missense Mutant Mice.” PLoS One, 2013, Vol. 8 No.3.

Liu, Y., Bao, X., Wang, D., and others. “Allelic Variations of Glut-1 Deficiency Syndrome: the Chinese Experience.” Pediatric Neurology. 2012 Jul., Vol. 47 No. 1, Pages 30-34.

Ozelius, L. “Clinical Spectrum of Disease Associated with ATP1A3 Mutations.” Lancet Neurology. 2012 Sept. Vol. 11 No. 9, Pages 741-743.

Rosewich, H, Thiele, H, Ohlenbusch, A, and others. “Heterozygous De-Novo Mutations in ATP1A3 in Patients with Alternating Hemiplegia of Childhood: A Whole-Exome Sequencing Gene-Identification Study.” Lancet Neurology, 2012 Sep. Vol. 11 No.9, Pages 764-73.

Rotstein M, Doran J, Yang, H, Ullner PM, Engelstad K, DeVivo DC. “Glut1 Deficiency and Alternating Hemiplegia of Childhood.” Neurology, 2009 Dec 8, Vol.73 No.23, Pages 2042-2044

Vuillaumier-Barrot, S., Panagiotakaki, E., Le Bizec, C., and others. “Absence of Mutation in the SLC2A1 Gene in a Cohort of Patients with Alternating Hemiplegia of Childhood.” Neuropediatrics. 2010. Dec. Vol. 41 No.6, Pages 267-269.

MEDICATION

Aishworiya, R., Low, P., Tay, S. “Alternating Hemiplegia of Childhood: Successful Treatment with Topiramate and Flunarizine, a Case Report.” Annals of Tropical Paediatrics. 2011. Vol. 31 No. 2, Pages 149-152.

Alexoudi, A, Schneider, SA. “Alternating Hemiplegia of Childhood and Rapid-onset Dystonia Parkinsonism are Allelic Disorders due to ATP1A3 Gene Mutations.” Movement Disorders. Oct. 2012, Page 1494.

Casaer P. “Flunarizine in Alternating Hemiplegia of Childhood: An International Study in 12 Children.” Neuropediatrics, 1987 Nov., Vol. 18 No. 4, Pages 91-95.

Chi, L, Zhao, X, Liu, X. “Alternating Hemiplegia of Childhood in Chinese Following Long-Term Treatment with Flunarizine or Topiramate.” The International Journal of Neuroscience. Sept. 2012, Vol. 122 No.9, Pages 506-510.

DiRosa, G., Spano, M., Pustorino, G., and others. “Alternating Hemiplegia of Childhood Successfully Treated with Topiramate: 18 Months of Follow-up.” Neurology. 2006 Jan. 10. Vol. 66 No.1, Pages 146-.

Haffejee S, Santosh PJ. “Treatment of Alternating Hemiplegia of Childhood with Aripiprazole.” Developmental Medicine and Child Neurology, 2009 Jan, Vol. 51 No. 1, Pages 74-77.

Jiang W, Chi Z, Ma L, Du B, Shang W, Guo H, Wu W. “Topiramate: A New Agent for Patients with Alternating Hemiplegia of Childhood.” Neuropediatrics, 2006 Aug, Vol. 37 No. 4, Pages 229-233.

Sasaki M, Sakuragawa N, Osawa M. “Long-term Effect of Flunarizine on Patients with Alternating Hemiplegia of Childhood in Japan.” Brain Development, 2001 Aug, Vol. 23 No. 5, page 303-305.

Siemes, H. “Rectal Chloral Hydrate for Alternating Hemiplegia of Childhood.” Developmental Medicine and Child Neurology. 1990 Oct. Vol. 32 No. 10. Pages 931-.

Silver K, Andermann F. “Alternating Hemiplegia of Childhood: A Study of 10 Patients and Results of Flunarizine Treatment.” Neurology, 1993 Jan, Vol. 43 No. 1, Pages 36-41.

Veneselli E, Biancheri R. “Alternating Hemiplegia of Childhood: Treatment of Attacks with Chloral Hydrate and Niaprazine.” European Journal of Pediatrics, 1997 February, Vol. 156 No. 2, PageS 157-158.

MIGRAINE

De Vries B, Stam AH, Beker F, Van den Maagdenberg AM, Vanmolkot KR, Laan L, Ginjaar IB, Frants RR, Lauffer H, Haan J, Haas JP, Terwindt GM. “CACNA1A Mutation Linking Hemiplegic Migraine and Alternating Hemiplegia of Childhood.” Cephalalgia, 2008 Aug, Vol. 28 No. 8, Pages 887-91.

Gaul C, Kraya T, Holle D, Benkel-Herrenbruck I, Schara U, Ebinger F. “Migraine Variants and Unusual Types of Migraine in Childhood.” Schmerz (German), April 2011, Vol. 25 No. 2, Pages 148-156.

Lance JW. “Is Alternating Hemiplegia of Childhood (AHC) A Variant of Migraine?” Cephalalgia 2000, Oct. Vol. 20 No. 8, Page 685.

Lebas A, Guyant-Marechal L, Hannequin D, Riant F. “Severe Attacks of Familial Hemiplegic Migraine, Childhood Epilepsy and ATP1A2 Mutation.” Cephalalgia, 2008, Vol. 28, Pages 774-777.

Swoboda KJ, Kanavakis E, Xaidara A, Johnson JE, Leppert MF, Schlesinger-Massart MB, Ptacek LJ, Silver K, Youroukos S. “Alternating Hemiplegia of Childhood or Familial Hemiplegic Migraine? A Novel ATP1A2 Mutation.” Annals of Neurology, 2004 June, Vol. 55 No. 6, Pages 884-887.

GENERAL

Arnold DL, Silver K, Andermann F. “Evidence for Mitochondrial Dysfunction in Patients with Alternating Hemiplegia of Childhood.” Annals of Neurology 1993 Jun, Vol.33 No.6, Pages 604-607.

Egan RA. “Ocular Motor Features of Alternating Hemiplegia of Childhood.” Journal of Neurophthalmology. 2002 June, Vol. 22 No. 2, Pages 99-101.

Fons, C, Campistol, J, Panagiotakaki, E, and others. “Alternating Hemiplegia of Childhood: Metabolic Studies in the Largest European Series of Patients.” European Journal of Paediatric Neurology. Jan 2012, Vol. 16 No.1, Pages 10-14.

Fons, C, Campistol, J, Narbona, J, Velazquez, R, Eiris, J, Garcia Penas, J. “Alternating Hemiplegia of Childhood in Spanish Population, Study of a Series of 17 Patients.” Med Clin (Barc). April 26, 2008, Vol. 13, Pages 577-579. (In Spanish)

Granata T, Vigevano F. “Alternating Hemiplegia: Italian White Book for Understanding andManaging this Rare Disease.” Associazione Italiana per la Sindrome di Emiplegia Alternante. Italy, 2007.

Incorpora G., Pavone P, Cocuzza M, Privitera M, Pavone L, Ruggieri M. “Neuronatal Onset of Bath-Induced Alternating Hemiplegia of Childhood.” European Journal of Paediatric Neurology. 2010 May, Vol. 14 No. 2, Pages 192-193.

Incorpora, G, Pavone, P, Polizzi, A, and others. “An 11-Year Follow-up Study of Neonatal- Onset, Bath-induced Alternating Hemiplegia of Childhood in Twins.” Journal of Child Neurology. 2012 May, Vol. 27 No. 5, Pages 657-662.

Kansagra, S, Mikati, Mohamad, Vigevano, F. “Chapter 85 – Alternating Hemiplegia of Childhood.” Handbook of Clinical Neurology. 2013, Vol. 112, Pages 821-826.

Mehrotra R. “General Anesthesia for a Patient with Alternating Hemiplegia of Childhood.” Canadian Journal of Anesthesia, 2005 Dec., Vol. 52 No. 10, Pages 1103-1104.

Mikati MA, Kramer U, Zupanc ML, Shanaha RJ. “Alternating Hemiplegia of Childhood: Clinical Manifestations and Long-Term Outcome.” Pediatric Neurology, 2000 Aug, Vol. 23 No. 2, Pages 134-141.

Mikati, MA. “Alternating Hemiplegia of Childhood.” Pediatric Neurology. 1999 Oct. Vol. 21 No. 4, Pages 764-.

Montirosso R, Ceppi E, D’aloisio C, Zucca C, Borgatti R. “International Classification of Functioning, Disability and Health in Subjects with Alternating Hemiplegia of Childhood.” Disability & Rehabilitation, 2009 Vol. 31 Suppl., Pages S108-15.

Nechay A, Stephenson JB. “Bath-Induced Paroxysmal Disorders in Infancy.” European Journal of Paediatric Neurology. 2009 May, Vol. 13 No. 3, Pages 203-208.

Neville BG, Ninan M. “The Treatment and Management of Alternating Hemiplegia of Childhood.” Developmental Medicine and Child Neurology, 2007 Oct, Vol. 49 No.10, Pages 777-80.

Panagiotakaki, E., Gobbi, G., Neville, B., and others. “Evidence of a Non-Progressive Course of Alternating Hemiplegia of Childhood: Study of a Large Cohort of Children and Adults.” Brain, a Journal of Neurology. 2010 Dec., Vol. 133 Pt. 12, Pages 3598-3610.

Rho JM, Chugani HT. “Alternating Hemiplegia of Childhood: Insights into its Pathophysiology.” Journal of Child Neurology, 1998 Jan, Vol. 3, Pages 39-45.

Rinalduzzi S, Valeriani M, Vigevano F. “Brainstem Dysfunction in Alternating Hemiplegia of Childhood: A Neurophysiological Study.” Cephalalgia, 2006 May, Vol. 26 No. 5, Pages 511-519.

Rubio, E, Rodriguez-Navarro, M, Garcia-Munoz, M, Alonso, J. “Major Ambulatory Surgery in a Patient with Alternating Hemiplegia of Childhood.” Rev Esp Anestesiol Reanim. Jan 2008, Pages 59-60. (In Spanish)

Saito, Y., Inui, t., Sakakibara, T., and others. “Evolution of Hemiplegic Attacks and Epileptic Seizures in Alternating Hemiplegia of Childhood.” Epilepsy Research. 2010 Aug, Vol. 90 No. 3, Pages 248-258.

Sasaki, M., Matsufuji, H., Inui, T., and others. “Absence of Small-Vessel Abnormalities in Alternating Hemiplegia of Childhood.” Brain & Development. 2011 May. Vol. 33 No. 5, Pages 390-393.

Sasaki M, Sakuma H, Fukushmia A, Yamada K, Ohnishi T, Matsuda H. “Abnormal Cerebral Glucose Metabolism in Alternating Hemiplegia of Childhood.” Brain Development, 2009 Jan., Vol. 31 No. 1, Pages 20-26.

Save, J, Poncelin, D, Auvin, S. “Caregiver’s Burden and Psychosocial Issues in Alternating Hemiplegia of Childhood.” Eur J Paediatr Neurol. May 11, 2013.

Shafer ME, Mayfield JW, McDonald F. “Alternating Hemiplegia of Childhood: A Study of  Neuropsychological Functioning.” Applied Neuropsychology. 2005 Vol. 12 No. 1, Pages 49- 56.

Shiota, N., Shimono, M., Tomioka, S., and others. “A Boy with Nystagmus, Refractory Dystonia and Apneic Attack Due to Alternating Hemiplegia of Childhood.” Brain and Development. 2007 Jul. Vol. 39 No. 4, Pages 285-288.

Sweney MT, Silver K, Gerard-Blanluet M, Pedespan JM, Renault F, Arzimanoglou A, Schlesinger-Massart M, Lewelt AJ, Reyna SP, Swoboda KJ. “Alternating Hemiplegia of Childhood: Early Characteristics and Evolution of a Neurodevelopmental Syndrome.” Pediatrics, 2009 Mar, Vol. 123 No. 3, Pages e534-541

Tatli, B., Aydinli, N., Caliskah, M., and others. “Clinical Features of Nine Patients with Alternating Hemiplegia of Childhood.” Journal of Paediatrics and Child Health. 2011 Oct. Vol. 47 No. 10, Pages 734-736.

Tenny, JR, Schapiro MB. “Child Neurology: Alternating Hemiplegia of Childhood.” Neurology, 2010 Apr 6, Vol. 74 No.14, Pages E57-E59.

Traut, M, Cavagnari, B, Mendez, JH, Amartino, H. “Alternating Hemiplegia of Childhood: A Case Report and Literature Review.” Arch Argent Pediatr, Oct. 2012. (In Spanish)

Villega, F., Picard, F., Espil-Taris, C., and others. “Benign Nocturnal Alternating Hemiplegia of Childhood: Two Cases with Positive Evolution.” Brain & Development. 2011 Jun. Vol. 33 No. 6, Pages 525-529.

Wagener-Schimmel, L, Nicolai, J. “Child Neurology” Benign Nocturnal Alternating Hemiplegia of Childhood.” Neurology. 2012 Oct, 30. Vol. 79 No. 18, Pages 161-163.

Winchester, S, Singh, P, Mikati, M. “Chapter 127 – Ataxia.” Handbook of Clinical Neurology. 2013, Vol. 112, Pages 1213-1217.

ALPHABETICAL BY AUTHOR’S LAST NAME

Aicardi J. “Alternating Hemiplegia of Childhood.” Chapter 24 Epilepsy and Movement Disorders. Renzo G, Andermann F, Hallett M. Cambridge University Press 2002, Pages 379-392.

Aishworiya, R., Low, P., Tay, S. “Alternating Hemiplegia of Childhood: Successful Treatment with Topiramate and Flunarizine, a Case Report.” Annals of Tropical Paediatrics. 2011. Vol. 31 No. 2, Pages 149-152.

Alexoudi, A, Schneider, SA. “Alternating Hemiplegia of Childhood and Rapid-onset Dystonia Parkinsonism are Allelic Disorders due to ATP1A3 Gene Mutations.” Movement Disorders. Oct. 2012, Page 1494.

Andermann F, Ohtahara S, Andermann E, Camfield P, Kobayashi K. “Infantile Hypotonia and Paroxysmal Dystonia: A Variant of Alternating Hemiplegia of Childhood.” Movement Disorders, 1994 Mar, Vol. 9 No. 2, Pages 227-229.

Arnold DL, Silver K, Andermann F. “Evidence for Mitochondrial Dysfunction in Patients with Alternating Hemiplegia of Childhood.” Annals of Neurology 1993 Jun, Vol. 33 No. 6, Pages 604-607.

Badoe, EV. “Alternating Hemiplegia in a Child Misdiagnosed as Intractable Epilepsy Successfully Treated with Aripiprazole: A Case Study.” West Afr J Med. Mar-Apr 2011, Pages 140-144.

Bassi MT, Bresolin N, Tonelli A. “A Novel Mutation in the ATP1A2 Gene Causes Alternating Hemiplegia of Childhood.” Journal of Medical Genetics, 2004, Vol. 41 Pages 621-628.

Boileau S, Vuillaume I, Sablonniere B, Marignier S, Des Portes V, Vallee L, Auvin S. “Absence of T378N Mutation of ATP1A2 Gene in Five Patients with Alternating Hemiplegia of Childhood.” Developmental Medicine and Child Neurology, 2008 Nov., Vol. 50 No. 11, Pages 879-880.

Casaer P. “Flunarizine in Alternating Hemiplegia of Childhood: An International Study in 12 Children.” Neuropediatrics, 1987 Nov., Vol. 18 No. 4, Pages 91-95.

Chi, L, Zhao, X, Liu, X. “Alternating Hemiplegia of Childhood in Chinese Following Long- Term Treatment with Flunarizine or Topiramate.” The International Journal of Neuroscience. Sept. 2012, Vol. 122 No.9, Pages 506-510.

Di Michele, M, Goubau, C, Waelkens, E, Thys, C, De Vos, R, Overbergh, L, Schyns, T, Buyse, G, Casaer, P, Van Geet, C, Freson, K. “Functional Studies and Proteomics in Platelets and Fibroblasts Reveal a Lysosomal Defect with Increased Cathepsin-dependent Apoptosis in ATP1A3 Defective Alternating Hemiplegia of Childhood.” Journal of Proteomics. May 13, 2013.

DiRosa, G., Spano, M., Pustorino, G., and others. “Alternating Hemiplegia of Childhood Successfully Treated with Topiramate: 18 Months of Follow-up.” Neurology. 2006 Jan. 10. Vol. 66 No. 1, Pages 146-.

De Vries B, Stam AH, Beker F, Van den Maagdenberg AM, Vanmolkot KR, Laan L, Ginjaar IB, Frants RR, Lauffer H, Haan J, Haas JP, Terwindt GM. “CACNA1A Mutation Linking Hemiplegic Migraine and Alternating Hemiplegia of Childhood.” Cephalalgia, 2008 Aug, Vol. 28 No. 8, Pages 887-91.

De Vries, B, Haan, J, Stam, AH, Vanmolkot, KR, Stoink, H, Laan, LA, Gill, DS, Pascual, J, Frants, RR, van den Maagdenberg, AM, Ferrari, MD. “Alternating Hemiplegia of Childhood: No Mutations in the Glutamate Transporter EAAT1.” Neuropediatrics. Oct 2006, Pages 302- 304.

Egan RA. “Ocular Motor Features of Alternating Hemiplegia of Childhood.” Journal of Neurophthalmology. 2002 June, Vol. 22 No. 2, Pages 99-101.

Fons, C, Campistol, J, Panagiotakaki, E, and others. “Alternating Hemiplegia of Childhood: Metabolic Studies in the Largest European Series of Patients.” European Journal of Paediatric Neurology. Jan 2012, Vol. 16 No.1, Pages 10-14.

Fons, C, Campistol, J, Narbona, J, Velazquez, R, Eiris, J, Garcia Penas, J. “Alternating Hemiplegia of Childhood in Spanish Population, Study of a Series of 17 Patients.” Med Clin (Barc). April 26, 2008, Vol. 13, Pages 577-579. (In Spanish)

Gaul C, Kraya T, Holle D, Benkel-Herrenbruck I, Schara U, Ebinger F. “Migraine Variants and Unusual Types of Migraine in Childhood.” April 2011, Vol. 25 No.2, Pages 148-156. (German)

Granata T, Vigevano F. “Alternating Hemiplegia: Italian White Book for Understanding and Managing this Rare Disease.” Associazione Italiana per la Sindrome di Emiplegia Alternante. Italy, 2007.

Haffejee S, Santosh PJ. “Treatment of Alternating Hemiplegia of Childhood with Aripiprazole.” Developmental Medicine and Child Neurology, 2009 Jan, Vol. 51 No. 1, Pages 74-77.

Heinzen, E, Swoboda, K, Hitomi, Y, and others. “De Novo Mutations in ATP1A3 Cause Alternating Hemiplegia of Childhood.” Nature Genetics, Sept. 2012, Vol. 44, No.9, Pages 1030-1034.

Incorpora G., Pavone P, Cocuzza M, Privitera M, Pavone L, Ruggieri M. “Neuronatal Onset of Bath-Induced Alternating Hemiplegia of Childhood.” European Journal of Paediatric Neurology. 2010 May, Vol. 14 No. 2, Pages 192-3.

Incorpora, G, Pavone, P, Polizzi, A, and others. “An 11-Year Follow-up Study of Neonatal- Onset, Bath-induced Alternating Hemiplegia of Childhood in Twins.” Journal of Child Neurology. 2012 May, Vol. 27 No. 5, Pages 657-662.

Inui, T, Saito, Y, Sakuma, H, and others. “Profiles of Blood Biomarkers in Alternating Hemiplegia of Childhood—Increased MMP-9 and Decreased Substance P Indicates its Pathophysiology.” Brain & Development. 2012, Mar., Vol. 34 No. 3, Pages 196-200.

Ishi A, Saito, Y, Mitsui, J, and others. “Identification of ATP1A3 Mutations by Exome Sequencing as the Cause of Alternating Hemiplegia of Childhood in Japanese Patients.” PloS one, 2013 Feb., Vol. 8 No. 2.

Jen JC, Wan J, Palos TP, Howard BD, Baloh RW. “Mutation in the Glutamate Transporter EAAT1 Causes Episodic Ataxia, Hemiplegia, and Seizures.” Neurology, 2005 Aug 23, Vol. 65 No. 4, Pages 529-534.

Jiang W, Chi Z, Ma L, Du B, Shang W, Guo H, Wu W. “Topiramate: A New Agent for Patients with Alternating Hemiplegia of Childhood.” Neuropediatrics, 2006 Aug, Vol. 37 No. 4, Pages 229-233.

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