Generated by All in One SEO v5.0.0.1, this is an llms.txt file, used by LLMs to index the site. # AHCF ## Sitemaps - [XML Sitemap](https://ahckids.org/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [Exciting News For The AHC Community!](https://ahckids.org/exciting-news-for-the-ahc-community/) - EXCITING NEWS FOR THE AHC COMMUNITY! 🚨 Aspartes Pharmaceuticals has announced that the FDA has granted Orphan Drug Designation and Rare Pediatric Disease Designation to ASP-001, an investigational formulation of flunarizine being developed specifically for Alternating Hemiplegia of Childhood (AHC). 💊 ASP-001 is an orally disintegrating tablet designed to dissolve in the mouth and is - [Webinnar Replay Link: Dr Suzanne DeBrosse Your Child’s AHC Genetic Results: What They Mean—and Why They Matter](https://ahckids.org/webinnar-replay-link-dr-suzanne-debrosse-your-childs-ahc-genetic-results-what-they-mean-and-why-they-matter/) - https://ahckids.org/webinnar-replay-…-why-they-matter/ Many individuals with Alternating Hemiplegia of Childhood (AHC) have a change, or mutation, in the ATP1A3 gene—but understanding what those results mean can feel overwhelming. Listen to this special webinar with Suzanne D. DeBrosse, MD, FACMG, as she helps families better understand the genetics behind AHC, what genetic testing can (and can’t) tell us, - [Making Telehealth Permanent](https://ahckids.org/making-telehealth-permanent/) - The AHC Foundation is proud to join organizations across the country in urging Congress to make Medicare telehealth access permanent. Telehealth has become an essential part of healthcare for many individuals and families living with rare diseases like Alternating Hemiplegia of Childhood (AHC), helping reduce travel burdens and improve access to specialists. Current Medicare telehealth - [Historic Day for the AHC Community](https://ahckids.org/historic-day-for-the-ahc-community/) - Pediatric Epilepsies & Rare CNS Gene Editing Platform (PERC) accelerates the development of precision genetic medicines for severe childhood neurologic disease. BAR HARBOR, ME (July 9, 2026) — The Jackson Laboratory (JAX) today announced it has been selected, with the Broad Institute and other partners, for an up to $34.5 million contract from the Advanced - [Family Reference Guide](https://ahckids.org/9646-2/) - Helping families better understand AHC. https://Familyreferenceguide.tiiny.site Last fall, the AHC Foundation was selected to participate in the Genetic Counseling Student Exchange (GCSX) Jumpstart Program through the Orphan Disease Center at the University of Pennsylvania. Today, we're proud to share the second educational resource to come from that collaboration—the AHCF Family Reference Guide. Developed by genetic - [AHCF Monthly Family Update](https://ahckids.org/ahcf-monthly-family-update/) - Something new from AHCF! Read the July AHCF Monthly Family Update here: https://ahcfmonthlyfamilyupdate.tiiny.site We're excited to introduce AHCF Monthly Family Updates—a new way to keep our community informed, connected, and supported throughout the year. Each month, we'll share timely news, educational resources, Foundation updates, and family support all in one place. Inside this month's update: - [AHC - Clinical Reference Guide](https://ahckids.org/ahc-clinical-reference-guide/) - Introducing the AHC Clinical Reference Guide https://ahcclinicalreferenceguide.tiiny.site/ Last fall, the AHC Foundation was selected to participate in the GCSX Jumpstart Program through the Orphan Disease Center at the University of Pennsylvania. Partnering with Taylor Salvigsen of the University of Pittsburgh Genetic Counseling Program, we set out to create the kind of educational resources our community - [Webinar Replay Link - Dr Mohamad Mikati - “What We've Learned from the outcome study of 115 Individuals with AHC"](https://ahckids.org/webinar-replay-link-dr-mohamad-mikati-what-weve-learned-from-the-outcome-study-of-115-individuals-with-ahc/) - Replay Link: https://accountingdepartment.wistia.com/s/ir33y49byi7i6ic The Natural History Study of AHC which was published recently has major implications for the care of AHC champions and for anticipated clinical trials. This study highlights, among other things, many prognostic factors that help chart the clinical course of specific patients, that can help families know what to expect and thus - [A New Step Forward for Our AHC Families](https://ahckids.org/a-new-step-forward-for-our-ahc-families/) - Some research doesn’t just move science forward — it moves hope forward. A new study announced earlier this month created the first C. elegans (tiny worm) models of AHC. The AHC Foundation, CureAHC and RareHope co-funded two phases of this multi-year project. While the science is complex, the message for families is simple: Researchers are - [AHCF Spring Newsletter](https://ahckids.org/ahcf-newsletter/) - Our newest AHCF newsletter shares the heart of our mission — supporting families, advancing research, and building a stronger future together. From exciting research updates and educational webinars to community stories and conference news, this issue highlights the incredible resilience and compassion within the AHC community. Thank you for continuing to walk this journey with - [RAD workshop attended by AHCF President Vicky Platt](https://ahckids.org/rad-workshop-attended-by-ahcf-president-vicky-platt/) - AHCF President Vicky Platt proudly represented the AHC community this week at the Global Genes/Rare Epilepsy Network RAD Workshop! 💙 Alongside Rebecca Smith from JAX Labs, Alex Sousa from Broad Institute, and Lacey Henderson, Vicky helped ensure the AHC voice was part of important conversations focused on advancing rare disease and epilepsy research, collaboration, and - [Sylvia Pollard joins AHCF Board of Directors](https://ahckids.org/sylvia-pollard-joins-ahcf-board-of-directors/) - Sylvia and her husband John joined the AHC community after their daughter Paige was diagnosed with Alternating of Hemiplegia (AHC). Their journey eventually led them to relocate to Houston to be near specialized care Paige needs. Many families know Sylvia as "Dr Mom" - A source of encouragement, honesty and support for caregivers navigating the - [Tiny Worms may hold key to treating AHC!](https://ahckids.org/tiny-worms-may-hold-key-to-treating-ahc/) - A major step forward for AHC research. Researchers at Brown University have developed and characterized a genetically engineered C. elegans model for ATP1A3-related disease that enables scalable drug screening across multiple patient variants. The work, led by Dr. Anne Hart and Diana Wall, represents an important advance toward accelerating therapeutic discovery in AHC. These models - [Webinar Replay Link -Denise Potter, RDN, Founder of Advanced Ketogenic Therapies](https://ahckids.org/webinar-replay-link-denise-potter-rdn-founder-of-advanced-ketogenic-therapies/) - Missed Denise Potter's webinar? It's now available to watch. When epilepsy is part of AHC, families are often told to try medication after medication, but rarely offered ketogenic therapy early. Why wait? Denise Potter, dietitian and founder of Advanced Ketogenic Therapies, explores how ketogenic therapy works, why it’s often misunderstood, and how it may support - [AHC and Epilepsy, Clarity and Confusion Webinar Replay link](https://ahckids.org/ahc-and-epilepsy-clarity-and-confusion-webinar-replay-link/) - Dr. Kevin Ess, a leading neurologist in Epilepsy and Alternating Hemiplegia of Childhood (AHC) shared insights from the front lines of research and care — what’s next for families and the path to better treatments. Replay Link https://bit.ly/48OnzFh - [Charli Chapai](https://ahckids.org/charli-chapai/) - [AHC Community Update from Dr Marcio Sotero](https://ahckids.org/ahc-community-update-from-dr-marcio-sotero/) - AHC Community Update!!! We're excited to share that families in Brazil are receiving wonderful clinical and research services with the help of AHCF Medical Advisory Board member, Marcio Sotero de Menezes. Dr. Sotero reports, "We had two wonderful clinics in São Paulo and Salvador. We saw lots of kids and some adults. The study is - [NORD State Report Card](https://ahckids.org/nord-state-report-card/) - Since 2015, evaluating all 50 states plus DC across 9 critical policy areas affecting the 30 million Americans living with rare diseases and their families. How does your state measure up? It is important to note the issues contained here in touch on several critical and relevant policy areas at the state level, but the - [Webinar Replay Link - How Your AHC Data Drives Research and Improves Care](https://ahckids.org/webinar-replay-link-how-your-ahc-data-drives-research-and-improves-care/) - Missed Dr. Nutan Sharma’s webinar? It’s now available to watch! Watch, learn, and be part of what comes next. Link: https://tinyurl.com/3efdn4sd Dr. Sharma is leading an incredible Natural History Study for children and adults with AHC—an essential first step in understanding how the disease evolves through puberty and into adulthood, and in preparing for future - [AISEA ETS - Associazione Italiana - Important News for the 𝐀𝐇𝐂 Community](https://ahckids.org/aisea-ets-associazione-italiana-important-news-for-the-𝐀𝐇𝐂-community/) - Important News for the 𝐀𝐇𝐂 Community The first international training course entirely dedicated to Alternating Hemiplegia of Childhood (AHC) and disorders caused by mutations in the ATP1A3 gene will take place on Friday, April 17, 2026 (Genoa-Italy) This event is organized and funded by A.I.S.EA ETS (the Italian AHC Association) in collaboration with the child - [Leading the Next Phase of AHC Research](https://ahckids.org/leading-the-next-phase-of-ahc-research/) - We are proud to announce a major investment in the future of AHC research. The AHC Foundation is committing over $300,000 to fund a prospective Natural History Study at Massachusetts General Hospital, led by Dr. Nutan Sharma. This study will expand the largest long-standing AHC patient data and bio-sample collection effort, identify measurable indicators of - [Eight Minutes - Thirty Years](https://ahckids.org/eight-minutes-thirty-years/) - Eight minutes. Thirty years. Thirty years of courage in hospital rooms. Thirty years of siblings becoming advocates. Thirty years of doctors and researchers refusing to give up. Thirty years of science moving forward because families never stopped believing. Created by a sibling of an AHC adult, this tribute tells our story in a way words - [Big news for the AHC community!](https://ahckids.org/big-news-for-the-ahc-community/) - On February 26, 2026, the Child Neurology Society named the IAHCRC natural history study on AHC as both Editor’s Choice and a “great example” of excellence in their journal. The study followed 115 individuals using standardized protocols and provides the most complete description to date of AHC’s natural history. The journal also featured one of - [🫀 Heart 2 Heart Webinar: Replay Link](https://ahckids.org/🫀-heart-2-heart-webinar-replay-link/) - If you missed the live session, the webinar replay link is right here! https://tinyurl.com/46k8kuma We will also be sharing additional materials soon, including follow-up Q&A and supporting resources. Thank you to Dr. Landstrom and Terralyn for helping move this vital conversation forward for our families. - [AHCF selected for (GCSX) Jumpstart Program](https://ahckids.org/ahcf-selected-for-gcsx-jumpstart-program/) - We’re excited to share that the Alternating Hemiplegia of Childhood Foundation has been selected to participate in the Genetic Counseling Student Exchange (GCSX) Jumpstart Program through the Orphan Disease Center at the University of Pennsylvania.This semester, we are pleased to partner with 𝗧𝗮𝘆𝗹𝗼𝗿 𝗦𝗮𝗹𝘃𝗶𝗴𝘀𝗲𝗻, a second-year genetic counseling student at the University of Pittsburgh.Through this - [Science to Support - Video Series](https://ahckids.org/science-to-support-video-series/) - Behind every research paper is a question families care deeply about: What does this mean for my child? https://www.facebook.com/reel/1394424725481147 Our President, Vicky Platt, has been part of the AHC community for more than 20 years — first as a mom to her daughter Emma, now 24, and always as a leader and advocate for families. - [AHCF Participates in a ground-breaking Florida health initiative.](https://ahckids.org/ahcf-participates-in-a-ground-breaking-florida-health-initiative/) - To kick off the New Year, the AHC Foundation participated in a program called, Sunshine Genetics. It is Florida’s state-funded genomic newborn screening (gNBS) research study coordinated by the Florida Institute for Pediatric Rare Diseases at Florida State University. This study will screen Floridian newborns for over 500 genetic conditions not currently screened as part - [Characterization of Sleep in Alternating Hemiplegia of Childhood](https://ahckids.org/characterization-of-sleep-in-alternating-hemiplegia-of-childhood/) - An International Survey: Few studies have investigated sleep features in people with alternating hemiplegia of childhood (AHC). In this study, we present a bespoke survey of individuals with AHC to characterize sleep disturbances in this condition. Methods A cross-sectional survey was disseminated through the UK and Italian AHC family associations, addressing their registered families with - [New Jointly Funded Research Takes Aim at Brain Instability in AHC](https://ahckids.org/new-jointly-funded-research-takes-aim-at-brain-instability-in-ahc/) - International AHC organizations are launching a new, multi-year research project led by Prof. dr. van den Maagdenberg at Leiden University Medical Centre to better understand spreading depolarization—abnormal waves of electrical activity in the brain that may drive severe and life-threatening episodes in AHC.New Jointly Funded Research Takes Aim at Brain Instability in AHC International AHC - [Dr Marcio Sotero Advocating for AHC in Brazil](https://ahckids.org/dr-marcio-sotero-advocating-for-ahc-in-brazil/) - Dr Marcio Sotero traveled to Brazil for an AHC-ATP1A3 Clinic in Sao Paulo at the Genome Institute of the Sao Paulo State University. Dr Sotero is a member of the AHCF Medical Advisory Board and continues to be an advocate for AHC! - [Dr David Liu Interviewed by 60 Minutes](https://ahckids.org/dr-david-liu-interviewed-by-60-minutes/) - Harvard chemist and molecular biologist David Liu invented gene editing tools that can correct and rewrite defective genes. His research could one day help hundreds of millions of people with genetic diseases like AHC and RDP https://cbsn.ws/4nKlpuU The whole story can be found here bit.ly/3XqASFE A little about Dr Liu: David R. Liu is the - [Pivotal Paper on AHC Just Published](https://ahckids.org/pivotal-paper-on-ahc-just-published/) - A collaborative international research article was just published in the November 2025 issue of Annals of the Child Neurology Society. Every single contributor to this paper deserves our thanks as this information our community has needed for a long time. This paper will be referred to by every AHC patient for years to come. The paper - [Knowledge mapping and emerging trends in pediatric hemiplegia research](https://ahckids.org/knowledge-mapping-and-emerging-trends-in-pediatric-hemiplegia-research/) - This bibliometric study spanning 1982-2025 provides an overview of research progress and identifies key hotspots in pediatric hemiplegia research. Pediatric hemiplegia is a significant neurological condition that impacts motor function and quality of life. This bibliometric analysis provides a comprehensive overview of research progress and identifies key hotspots in pediatric hemiplegia research, revealing the field's - [Insights From a Decade of Discovery and Collaboration - AHC & ATP1A3 related diseases](https://ahckids.org/insights-from-a-decade-of-discovery-and-collaboration-ahc-atp1a3-related-diseases/) - This report presents key insights from the 2022 annual conference held in Edinburgh, commemorating the 10th anniversary of the discovery of ATP1A3 variants in alternating hemiplegia of childhood (AHC). This milestone event marked a decade of rapid advancements in research and clinical understanding, bringing together international experts and those with lived experience to reflect on - [AHC Advocacy in Action](https://ahckids.org/ahc-advocacy/) - On November 4th, AHCF joined over 450 organizations (health care providers, digital health innovators, and patient and provider advocacy organizations) in sending a letter to Congress. The letter pressed Congress to immediately act on a long-term telehealth fix in its next legislative package to ensure stability and provide clarity for patients, providers, and the health - [Riley Duarte](https://ahckids.org/riley-duarte/) - [New Case Report: Exploring a Novel Approach for AHC Treatment](https://ahckids.org/new-research-article-clinical-improvement-in-a-case-of-alternating-hemiplegia-of-childhood-after-cerebral-lymphatic-drainage/) - An exploratory study evaluating the effects of the Muscular Acoustic Modulator (MAM) on a single patient with AHC. Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12493932/ This exploratory study evaluated the effects of the Muscular Acoustic Modulator (MAM) on a single patient with AHC treated for one year. The treatment was associated with a notable reduction in the frequency and duration - [Latest insights from published AHC research - Ketogenic Diet](https://ahckids.org/latest-insights-from-published-ahc-research-ketogenic-diet/) - AHCF is happy to share the latest insights from published AHC research."Ketogenic diet for alternating hemiplegia of childhood: Case report and literature review. Yang Y, Liu P, Li P, Huang Y, Hu S. Medicine (Baltimore). 2025 Oct 3;104(40):e44993. Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12499699/ Short Statement: Documents the positive effects of the ketogenic diet in patients with AHC. Summary: - [Child Neurology Annual Caregiver Survey](https://ahckids.org/child-neurology-annual-caregiver-survey/) - Each year, CNF asks caregivers and clinicians to tell us what support is most needed right now. Your input guides where we focus next. For Caregivers • Your answers are anonymous and will directly shape the programs and support CNF provides for families. • The survey takes about 10 minutes and is open through December - [Summary of the 13th ATP1A3 in Disease Symposium](https://ahckids.org/summary-of-the-13th-atp1a3-in-disease-symposium/) - Cairns, Australia – September 15–16, 2025 The 13th ATP1A3 in Disease Symposium was held in Cairns, Australia, on September 15–16, 2025. The meeting took place just before the triennial P-type ATPase Symposium. The ATP1A3 meeting was organized by Dr. Melody Li from the Florey Institute of Neuroscience and Mental Health in Melbourne, while the - [Brooke Tasi](https://ahckids.org/brooke-tasi/) - [Kathryn Marszalek](https://ahckids.org/kathryn-marszalek/) - [Kiley Andrasco](https://ahckids.org/kiley-andrasco/) - [Jocelyn Gates](https://ahckids.org/jocelyn-gates/) - [Lainey May Matuska](https://ahckids.org/lainey-may-matuska/) - [Sean Gerber](https://ahckids.org/sean-gerber/) - [Tanner Rosebrook](https://ahckids.org/tanner-rosebrook/) - [Alice Silver](https://ahckids.org/alice-silver/) - [Ellie Williams](https://ahckids.org/ellie-williams/) - [Whitney (Wit) Mir](https://ahckids.org/whitney-wit-mir/) - [Research Update](https://ahckids.org/research-update/) - [Dr. George gave a great talk on ASO Research](https://ahckids.org/dr-george-gave-a-great-talk-on-aso-research/) - Dr. George gave a great talk on ASO Research back in October. If you missed it you can view it now! https://youtu.be/LLC6qwLnG-w Subscribe to our YouTube Channel while you are there and check out our playlists with all the most recent research updates and other educational resources! - [Wish Come True Co. has generously offered to provide free princess videos for people with AHC! ](https://ahckids.org/wish-come-true-co-has-generously-offered-to-provide-free-princess-videos-for-people-with-ahc/) - Izzie Duval, founder and owner of Wish Come True Co., understands the complex realities of AHC. As an AHCF volunteer and AHC mom to Dallas, age 4, she is passionate about using her talent and growing business to bring joy to people with AHC and their families. - [AHC is a 1 in a million diagnosis, making it an ultra-rare disease!](https://ahckids.org/ahc-is-a-1-in-a-million-diagnosis-making-it-an-ultra-rare-disease/) - AHC is a 1 in a million diagnosis, making it an ultra-rare disease! - [Research Update August 2023](https://ahckids.org/research-update-august-2023/) - Your donations are being put to good use! Multiple projects are currently underway to advance AHC research and ultimately cure AHC. Read a detailed report of current projects being funded by the AHC organizations here: http://ahckids.org/wp-content/uploads/2023/08/Research_CommunityUpdate_20230808.pdf - [Research Video Series - Alexander Sousa](https://ahckids.org/research-videos-series-alexander-sousa/) - Alexander Sousa joins our research series to discuss how the application of biological tools that make precise changes in DNA, gene editing, might help cure AHC. If you missed it you can view it now! https://youtu.be/nBz3pIm_V2Q?feature=shared Subscribe to our YouTube Channel while you are there and check out our playlists with all the most recent research updates and other educational resources! - [Research Video Series - Dr. George](https://ahckids.org/research-video-series-george/) - Dr. All George explains his involvement in pursuing a cure or treatment for AHC. He and his team are increasing our understanding of the basic molecular and cellular defects that cause the disease. Secondly, they are exploring the feasibility and potential effectiveness of specific genetic and molecular techniques that could be, one day, therapeutically valuable. - [AHCF Summer Family Newsletter - Family Meeting Recap and More](https://ahckids.org/ahcf-summer-family-newsletter-family-meeting-recap-and-more/) - Our latest Family Newsletter is here — and it’s a very special one. It’s filled with updates, resources, and stories that speak to the heart of our community. From emotional reflections to important news, this issue is packed with information you won’t want to miss. Take a few moments to read, connect, and feel the - [Two Groundbreaking Wearable Studies for AHC](https://ahckids.org/two-groundbreaking-wearable-studies-for-ahc/) - RARE Hope, Cure AHC, and the AHC Foundation are proud to announce two groundbreaking wearable studies—developed and supported together—to advance care and research for AHC. • University of Chicago will study autonomic dysfunction, collecting data on heart rate and other body functions to better understand how AHC impacts these systems. • Massachusetts General Hospital (MGH) - [Breakthrough Research - Opens Door to Repairing Underlying Genetic Causes](https://ahckids.org/prime-editing-treats-childhood-brain-disease-in-mice/) - Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy. By the time they are a few months old, infants born with alternating hemiplegia of childhood (AHC) begin experiencing - [New Article - Mouse Model for Ultra-Rare Disorders](https://ahckids.org/new-article-mouse-model-for-ultra-rare-disorders/) - Check out a new article on the exciting AHC work going on at The Jackson Laboratory. It covers the newly published paper in Neurobiology of Disease from Markus Terrey and Kat Lutz. The research comes from JAX's Rare Disease Translational Center, which focuses on bridging the gap between genetic research and clinical treatment by working - [AHC Families Needed for Research Project](https://ahckids.org/ahc-families-needed-for-research-project/) - Calling AHC parents & guardians! Genetic counseling student, Rae Dwyer -Case Western Reserve University, is conducting research interviews to better understand the AHC journey—from diagnosis to daily life. Your story could help shape the future of care and advocacy. Learn more here. If you are interested in participating, please complete the survey: take survey. Contact - [AHC & Status Epilepticus Paper Just Published](https://ahckids.org/ahc-status-epilepticus-paper-just-published/) - Title: Practical management of repeated life-threatening status epilepticus in Alternating Hemiplegia of Childhood: Case report and literature review. Epileptic Disord. 2025 May 14. A team of Italian researchers published results from an AHC study on status epilepticus. The report aims to illustrate a comprehensive treatment approach and clinical management of an AHC patient with multiple - [New - D801N & E815K Mouse Info from Jackson Laboratory & AHC Experts](https://ahckids.org/d801n-e815k-mouse-info-from-jackson-laboratory-ahc-experts/) - Title: Alternating hemiplegia of childhood associated mutations in Atp1a3 reveal diverse neurological alterations in mice. Neurobiol Dis. 2025 May 15 The paper reports on how the mouse data reveals the presence but also the differential impact of the p.D801N and p.E815K variants on disease in AHC. Relevant alterations such as spontaneous and stress-induced paroxysmal episodes, motor - [New Research Alert: AHC & the Heart](https://ahckids.org/new-research-alert-ahc-the-heart/) - A major international study has just been published, exploring how ATP1A3 variants affect heart function in people with AHC. The multi-center case-control study spanned 12 centers across 10 countries, analyzing 148 individuals with AHC and 74 controls. The key finding: nearly 70% of individuals with the D801N variant had short QT intervals—a condition linked to - [Wear Your Support for a Cure - AHC Store is Live](https://ahckids.org/wear-your-support-for-a-cure-ahc-store-is-live/) - Big news: our online store is LIVE — and it’s packed with bold designs and powerful messages for the AHC community! 🎉 Help us spread the word by shopping, sharing, and spreading awareness for the community that never gives up! Shop today. - [Connect for a Cure! Win Prizes!](https://ahckids.org/connect-for-a-cure/) - Share the June AHCF Family Meeting on social media. Win prizes. Check out the details! Join this fun contest to help us all connect in our mission to find a cure. Whether you’re a parent, advocate, researcher, or ally—your voice matters. Together, we can connect for a cure. Tag a friend. Repost this. Use #ConnectforaCure. - [Early Bird Registration Ends April 30th!](https://ahckids.org/early-bird-registration-ends-april-30th/) - Early Bird Registration Ends April 30th! Don't miss your chance to join the rare disease community at a lower rate! This is more than a conference—it’s where families, advocates, and researchers come together to share hope, knowledge, and connection. Be there. Be informed. Be inspired. Secure your spot before prices go up! https://ahckids.org/family-meeting/ - [Family Fun in Cincinnati](https://ahckids.org/8217-2/) - Couple the Family Meeting with an unforgettable vacation with Family Fun in Cincinnati: A Perfect Getaway! Looking for the perfect family vacation? Cincinnati is a hidden gem packed with unforgettable experiences for kids and parents alike! Explore & Learn – From hands-on exhibits at the Cincinnati Museum Center to the wonders of the Newport Aquarium, every - [AHCF Spring Newsletter is here!](https://ahckids.org/ahcf-spring-newsletter-is-here/) - General Family Newsletter – Get Involved & Make an Impact! Our latest Family Newsletter is here! In this edition, we’re sharing family support resources, new doctors, helpful guides, and an important call to action: We need YOU to help fundraise!Every effort—big or small—helps drive research, support families, and bring us closer to better treatments. Start your - [2023 ATP1A3 Symposium in Chicago Summarized](https://ahckids.org/2023-atp1a3-symposium-in-chicago-summarized/) - Read more about the ATP1A3 Symposium The 12th Symposium will be held in Barcelona, Spain November 14-15, 2024. - [Big News from Liu Lab – Gene Editing Project](https://ahckids.org/big-news-from-liu-lab-gene-editing-project/) - Dear Friends and Families of the AHC Patient Community: We want to update you on some exciting news related to our gene editing project. Over the last several months, the Liu Lab has tested their gene editing strategy in AHC mice at the Jackson Laboratory. Preliminary results are encouraging. The Liu team has found that ## Pages - [Home](https://ahckids.org/) - [Newsroom](https://ahckids.org/newsroom/) - Our Medical Advisory Board members, Dr. Sho Yano and Dr. Ken Silver, did a joint presentation on May 4, 2024, on the latest information on AHC related to ATP1A3 at Lurie Children’s Hospital for the Neurology department. They did a great job introducing the complexities of ATP1A3 and educating the staff about AHC. One topic . - [Genetic Discovery](https://ahckids.org/genetic-discovery/) - [Road Map to AHC - Human Phenotype Ontology](https://ahckids.org/research/resources/road-map-to-ahc-human-phenotype-ontology/) - [Known Mood Disorders Associated With AHC](https://ahckids.org/research/resources/known-mood-disorders/) - [Gene Therapy Glossary](https://ahckids.org/research/resources/gene-therapy-glossary/) - [Flunarizine](https://ahckids.org/research/resources/flunarizine/) - [Comparison of AHC Mouse Models](https://ahckids.org/research/resources/comparison-of-ahc-mouse-models/) - [AHC Publication Hub](https://ahckids.org/research/resources/ahc-publication-hub/) - [AHC Infographics](https://ahckids.org/research/resources/ahc-infographics/) - [AHC Glossary](https://ahckids.org/research/resources/ahc-glossary/) - [Resources](https://ahckids.org/research/resources/) - [Research Collaboration](https://ahckids.org/research/collaboration/) - [Partnerships](https://ahckids.org/research/researcher-information/partnerships/) - [Funding Awards & Submission Process](https://ahckids.org/research/researcher-information/awards-process/) - [For Researchers](https://ahckids.org/research/researcher-information/) - [AHC Research Strategy](https://ahckids.org/research/strategy/) - [Research & Resources](https://ahckids.org/research/) - [AHC Research Projects](https://ahckids.org/research/projects/) - [Webinar Series](https://ahckids.org/webinar-series/) - [For Families](https://ahckids.org/for-families/) - [Volunteer](https://ahckids.org/volunteer/) - [Privacy Policy](https://ahckids.org/privacy-policy-2/) - [Lynn Egan Family Grant](https://ahckids.org/family-grant/) - [The AHC Foundation Mission](https://ahckids.org/our-mission-values/) - [For Families Resources](https://ahckids.org/for-families/resources/) - [05 - Our Impact](https://ahckids.org/05-our-impact/) - [Our Leadership](https://ahckids.org/our-leadership/) - [Impact Statement](https://ahckids.org/impact-statement/) - [Current Campaigns](https://ahckids.org/current-campaigns/) - [Home (Backup 2025-10-19)](https://ahckids.org/home-backup-2025-10-19/) - [Media Toolkit](https://ahckids.org/media-toolkit/) - [Home (Backup 2025-03-04)](https://ahckids.org/home-backup-20250304/) - [Our Impact](https://ahckids.org/our-impact/) - [06 - Volunteer](https://ahckids.org/06-volunteer/) - [Get Involved in the Fight to End AHC](https://ahckids.org/get-involved/) - [Ways to Give](https://ahckids.org/ways-to-give/) - [Fundraise for AHCF](https://ahckids.org/start-a-personal-fundraise/) - [Family Meeting](https://ahckids.org/family-meeting/) - Join us for the 15th AHCF Family Meeting! The meeting will take place in the Cincinnati, OH area Thursday June 19th through Saturday June 21st. Join us as we get energized by the wonderful support of our AHCF community! - [09 - Newsroom](https://ahckids.org/09-newsroom/) - [Symptoms](https://ahckids.org/learn-about-ahc/symptoms/) - [Understanding Behavior and AHC](https://ahckids.org/learn-about-ahc/understanding-behavior-and-ahc/) - [Contact Us](https://ahckids.org/contact-us/) - [Learn About AHC](https://ahckids.org/learn-about-ahc/) - [Connect with Us and Care Tips](https://ahckids.org/for-families/connect-with-us/) - [Crisis Intervention](https://ahckids.org/crisis-intervention/) - [Treatments](https://ahckids.org/treatments/) - [Therapies](https://ahckids.org/therapies/) - [Financial Information](https://ahckids.org/financial-information/) - [Triggers & Types of Attack](https://ahckids.org/triggers-types-of-attack/) - [Getting Started](https://ahckids.org/getting-started/) - [Genes Associated with AHC](https://ahckids.org/genes-associated-with-ahc/) - [Disorders Associated with AHC](https://ahckids.org/disorders-associated-with-ahc/) - [Clinical Spectrum of ATP1A3](https://ahckids.org/clinical-spectrum-of-atp1a3/) - [Donate](https://ahckids.org/donate/) - [07 - Donate](https://ahckids.org/07-donate/) - [Newly Diagnosed](https://ahckids.org/for-families/newly-diagnosed/) - [03 - Patient Care Overview](https://ahckids.org/03-patient-care-overview/) - [Join Our Community](https://ahckids.org/join-our-community/) - [Human Phenotype Ontology](https://ahckids.org/human-phenotype-ontology/) - [Gene Therapy FAQ](https://ahckids.org/gene-therapy-faq/) - [AHC Overview](https://ahckids.org/for-families/overview/) - [Family Meetings](https://ahckids.org/family-meetings/) - [Medical Advisory Board](https://ahckids.org/medical-advisory-board/) - [ATP1A3 & ATP1A2 Basics](https://ahckids.org/atp1a3-atp1a2-basics/) - [About the Foundation](https://ahckids.org/about-the-foundation/) - [ATP1A3 Symposium](https://ahckids.org/atp1a3-symposium/) - [Test Page](https://ahckids.org/test-page/) - [AHC Glossary](https://ahckids.org/ahc-glossary/) - [Apply for a Research Grant](https://ahckids.org/apply-for-a-research-grant/) - [Types of Movement](https://ahckids.org/types-of-movement/) - [Care Plans](https://ahckids.org/care-plans/) - [Caregiver Self-Care](https://ahckids.org/caregiver-self-care/) - [AHC Clinics in the United States](https://ahckids.org/ahc-clinics-in-the-united-states/) - [Sample Page](https://ahckids.org/sample-page/) - [Our History](https://ahckids.org/our-history/) - [Gene Therapy Glossary](https://ahckids.org/gene-therapy-glossary/) - [Volunteer Form](https://ahckids.org/volunteer-form/) - [Family Grant Application](https://ahckids.org/family-grant-application/) - [Join Our Family Directory](https://ahckids.org/join-our-family-directory/) - [FAQs & Glossaries](https://ahckids.org/faqs-glossaries/) - [AHCF Medical Research & Resources](https://ahckids.org/ahcf-medical-research-resources/) - [04 - Medical Research & Resources](https://ahckids.org/04-medical-research-resources/) - [Past Projects](https://ahckids.org/past-projects/) - [Intro to Gene Therapy](https://ahckids.org/intro-to-gene-therapy/) - [04 - Resources Directory](https://ahckids.org/04-resources-directory/) - [08 - Current Campaigns](https://ahckids.org/08-current-campaigns/) - [Family Meeting Archive](https://ahckids.org/family-meeting-archive/) - [Terms & Conditions](https://ahckids.org/terms-conditions/) ## Resources - [Tranquility incontinence resources- disposable briefs and liner pads for children and adults](https://ahckids.org/resources/tranquility-incontinence-resources-disposable-briefs-and-liner-pads-for-children-and-adults/) - Tranquility incontinence resources- disposable briefs and liner pads for children and adults https://tranquilityproducts.com - [Test Resource](https://ahckids.org/resources/test-resource/) - [Successful Corticosteroid Treatment of Refractory Spontaneous Vasoconstriction of Extracranial Internal Carotid and Coronary Arteries](https://ahckids.org/resources/successful-corticosteroid-treatment-of-refractory-spontaneous-vasoconstriction-of-extracranial-internal-carotid-and-coronary-arteries/) - Takeuchi M, Saito K, Kajimoto K, Nagatsuka K. “Successful Corticosteroid Treatment of Refractory Spontaneous Vasoconstriction of Extracranial Internal Carotid and Coronary Arteries.” The Neurologist (July 2016): 55-57. - [Alternating Hemiplegia of Childhood: ATP1A3 Gene Analysis in 16 Patients](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-atp1a3-gene-analysis-in-16-patients-2/) - Ulate-Campos A., Fons C, Campistol J. Martorell L, Cancho-Cadela R, Eiris J, Lopez-Laso E, Pineda M, Sans A, Velazquez R. “Alternating Hemiplegia of Childhood: ATP1A3 Gene Analysis in 16 Patients.” Med Clin. (April 23, 2014). (in Spanish) - [Publication Hub](https://ahckids.org/resources/publication-hub/) - The AHCF Publication Hub is a centralized platform for published literature regarding AHC. The Publication Hub is an excellent resource for anyone seeking the latest information about AHC research and topics related to this rare disease. If you have any comments or suggestions, please contact our Vice President of Research listed in the Board of - [Sibelium Insert](https://ahckids.org/resources/sibelium-insert/) - Drug information insert with the medication Sibelium. Sibelium is the generic pharmaceutical name for Flunarizine. - [Physician letter to accompany medication](https://ahckids.org/resources/physician-letter-to-accompany-medication/) - Your physician can use this letter template to create an accompaniment letter for your child's AHC medication - [Parent letter to accompany medication](https://ahckids.org/resources/parent-letter-to-accompany-medication/) - You can use this letter template to create an accompaniment letter for your child's AHC medication - [Rare-X Data Collection](https://ahckids.org/resources/rare-x-data-collection/) - The AHC community is partnering with RARE-X, a 501(c)(3) nonprofit organization, to build a Data Collection Program for AHC families. Participating in the AHC Data Collection Program will help accelerate research and the development of new drugs, devices, and other therapies. The AHC Community is building the AHC Data Collection Program to … Inform researchers - [ER Protocol](https://ahckids.org/resources/er-protocol/) - The AHC Foundation has published an Emergency Room Protocol. This document intends to educate doctors unfamiliar with AHC and your child's specific medical needs. Especially in this time of COVID-19 viral infections where your child may need to be admitted for treatment, this document will accompany your child and be passed off to caregivers for - [AAV Project](https://ahckids.org/resources/aav-project/) - Transgene therapy is another avenue of research that we are pursuing. - [Gene Editing Project](https://ahckids.org/resources/gene-editing-project/) - We are working with top scientists to edit out the mutation that causes AHC - [Natural History Database](https://ahckids.org/resources/natural-history-database/) - The natural history database is getting an update, and we need your help - [Antisense Oligonucleotides](https://ahckids.org/resources/antisense-oligonucleotides/) - ASO project description and what is needed going forward - [TOP 10 AHC Research Papers](https://ahckids.org/resources/top-10-ahc-research-papers/) - Here is a list of the top 10 most influential papers ever published on AHC. Heinzen EL, Swoboda KJ, Hitomi Y, et al. De novo mutations in ATP1A3 cause alternating hemiplegia of childhood. Nat Genet. 2012; 44:1030–1034. Jasien J, Bonner M, D’Alli R, Mikati M, et al. Cognitive, Adaptive, and Behavioral Profiles and Management of - [AHC Bibliography](https://ahckids.org/resources/ahc-bibliography/) - The AHC Foundation is pleased to provide the AHC community with a list of research articles published over the years on AHC-related topics. While this bibliography is in no way complete, it is a comprehensive record of academic and scientific publications relevant to our community. When a full text version of the article is available - [Monocular Nystagmus in a Patient with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/monocular-nystagmus-in-a-patient-with-alternating-hemiplegia-of-childhood/) - Tello J, Ruiz I, Herrera L, Miranda A, Alid P, Troncoso M. “Monocular Nystagmus in a Patient with Alternating Hemiplegia of Childhood.” Neurology. 2019 Aug 20;93(8):361. No Abstract - [NORD](https://ahckids.org/resources/nord/) - Patient advocacy organization dedicated to individuals with rare diseases. NORD - [Home equipment and supplies assistance.](https://ahckids.org/resources/home-equipment-and-supplies-assistance/) - Home equipment and supplies assistance. https://oley.org/general/recommended_links.asp?cc=40782 - [hild Neurology: Benign Nocturnal Alternating Hemiplegia of Childhood](https://ahckids.org/resources/hild-neurology-benign-nocturnal-alternating-hemiplegia-of-childhood/) - Wagener-Schimmel L, Nicolai J. “Child Neurology: Benign Nocturnal Alternating Hemiplegia of Childhood.” Neurology 79, no. 18 (October 30, 2012): 161-163. - [Alternating Hemiplegia of Childhood in a Person of Malay Ethnicity with Diffusion Tensor Imaging Abnormalities](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-a-person-of-malay-ethnicity-with-diffusion-tensor-imaging-abnormalities/) - Tan AH, Ong TL, Ramli N, Tan LK, Lim JL, Azhan MA, Ahmad-Annuar A, Ibrahim KA, Abdul-Aziz Z, Ozelius LJ, Brashear A, Lim SY. “Alternating Hemiplegia of Childhood in a Person of Malay Ethnicity with Diffusion Tensor Imaging Abnormalities.” Journal of Movement Disorders. 2019 May; 12(2): 132-134. Fulltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547042/ - [Clinical Features of Nine Patients with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/clinical-features-of-nine-patients-with-alternating-hemiplegia-of-childhood/) - Tatli B, Aydinli N, Caliskah M, et al. “Clinical Features of Nine Patients with Alternating Hemiplegia of Childhood.” Journal of Paediatrics and Child Health 47, no. 10 (October 2011): 734-736. - [Child Neurology: Alternating Hemiplegia of Childhood](https://ahckids.org/resources/child-neurology-alternating-hemiplegia-of-childhood/) - Tenney, JR, Schapiro MB. “Child Neurology: Alternating Hemiplegia of Childhood.” Neurology 74, no.14 (April 6, 2010): E57-E59. - [Alternating Hemiplegia of Childhood: A Case Report and Literature Review](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-a-case-report-and-literature-review/) - Traut M, Cavagnari B, Mendez JH, Amartino H. “Alternating Hemiplegia of Childhood: A Case Report and Literature Review.” Arch Argent Pediatr (October 2012). (In Spanish) - [Alternating Hemiplegia of Childhood with a De Novo Mutation in APT1A3 and Changes in SLC2A1 Responsive to Ketogenic Diet](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-with-a-de-novo-mutation-in-apt1a3-and-changes-in-slc2a1-responsive-to-ketogenic-diet-2/) - Ulate-Campos A, Fons C, Artuch R, Castejon E, Martorell L, Ozelius L, Pascual J, Campistol, J. “Alternating Hemiplegia of Childhood with a De Novo Mutation in APT1A3 and Changes in SLC2A1 Responsive to Ketogenic Diet.” Pediatric Neurology (December 6, 2013). - [Assessment of Acute Motor Deficit in the Pediatric Emergency Room](https://ahckids.org/resources/assessment-of-acute-motor-deficit-in-the-pediatric-emergency-room/) - Vasconcelos MM, Vasconcelos LGA, Brito AR. “Assessment of Acute Motor Deficit in the Pediatric Emergency Room.” Jornal de Pediatria, 93, supp. 1 (November-December 2017): 26-35. - [Alternating Hemiplegia in Childhood: A Report of Eight Patients with Complicated Migraine Beginning in Infancy](https://ahckids.org/resources/alternating-hemiplegia-in-childhood-a-report-of-eight-patients-with-complicated-migraine-beginning-in-infancy-2/) - Verret S and JC Steele. “Alternating Hemiplegia in Childhood: A Report of Eight Patients with Complicated Migraine Beginning in Infancy.” Pediatrics 47 (1971): 675-680. - [Benign Nocturnal Alternating Hemiplegia of Childhood: Two Cases with Positive Evolution](https://ahckids.org/resources/benign-nocturnal-alternating-hemiplegia-of-childhood-two-cases-with-positive-evolution/) - Villega F, Picard F, Espil-Taris C, et al. “Benign Nocturnal Alternating Hemiplegia of Childhood: Two Cases with Positive Evolution.” Brain & Development 33, no. 6 (June 2011): 525-529. - [Somatosensory System Hyperexcitability in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/somatosensory-system-hyperexcitability-in-alternating-hemiplegia-of-childhood/) - Vollono C, Rinalduzzi S, Milliucci R, Vigevano F, Valerianai M. “Somatosensory System Hyperexcitability in Alternating Hemiplegia of Childhood.” Eur J Neurol. 2014 Dec; 21(12): 1478-e97. - [Chapter 127 – Ataxia](https://ahckids.org/resources/chapter-127-ataxia/) - Winchester S, Singh P, Mikati M. “Chapter 127 – Ataxia.” Handbook of Clinical Neurology 112 (2013): 1213-1217. - [Clinical Characteristics of Alternating Hemiplegia of Childhood in 13 Patients](https://ahckids.org/resources/clinical-characteristics-of-alternating-hemiplegia-of-childhood-in-13-patients/) - Zhang Y, Sun W, Qin J, Jiang Y, Wu X. “Clinical Characteristics of Alternating Hemiplegia of Childhood in 13 Patients.” Chinese Journal of Pediatrics 41, no. 9: 680-683. - [Alternating Hemiplegia of Childhood in Two Adult Patients with a Mild Syndrome](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-two-adult-patients-with-a-mild-syndrome/) - Polanowska K, Dziezyc K, Rosewich H, Ohlenbusch A, Seniow J. “Alternating Hemiplegia of Childhood in Two Adult Patients with a Mild Syndrome.” Cognitive and Behavioral Neurology. Dec 2018; 31(4): 214-219. Abstract: https://insights.ovid.com/pubmed?pmid=30562231 - [Alternating Hemiplegia of Childhood: Insights into its Pathophysiology](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-insights-into-its-pathophysiology/) - Rho JM, Chugani HT. “Alternating Hemiplegia of Childhood: Insights into its Pathophysiology.” Journal of Child Neurology 3 (January 1998): 39-45. - [Brainstem Dysfunction in Alternating Hemiplegia of Childhood: A Neurophysiological Study](https://ahckids.org/resources/brainstem-dysfunction-in-alternating-hemiplegia-of-childhood-a-neurophysiological-study-2/) - Rinalduzzi S, Valeriani M, Vigevano F. “Brainstem Dysfunction in Alternating Hemiplegia of Childhood: A Neurophysiological Study.” Cephalalgia 26, no. 5 (May 2006): 511-519. - [Major Ambulatory Surgery in a Patient with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/major-ambulatory-surgery-in-a-patient-with-alternating-hemiplegia-of-childhood/) - Rubio E, Rodriguez-Navarro M, Garcia-Munoz M, Alonso J. “Major Ambulatory Surgery in a Patient with Alternating Hemiplegia of Childhood.” Rev Esp Anestesiol Reanim (January 2008): 59-60. (In Spanish) - [Evolution of Hemiplegic Attacks and Epileptic Seizures in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/evolution-of-hemiplegic-attacks-and-epileptic-seizures-in-alternating-hemiplegia-of-childhood/) - Saito Y, Inui T, Sakakibara T, et al. “Evolution of Hemiplegic Attacks and Epileptic Seizures in Alternating Hemiplegia of Childhood.” Epilepsy Research 90, no. 3 (August 2010): 248-258. - [A Case of Alternating Hemiplegia of Childhood with Cerebellar Atrophy](https://ahckids.org/resources/a-case-of-alternating-hemiplegia-of-childhood-with-cerebellar-atrophy/) - Saito Y, Sakuragawa N, Sasaki M, Sugai K, Hashimoto T. “A Case of Alternating Hemiplegia of Childhood with Cerebellar Atrophy.” Pediatric Neurology 19, no. 1 (July 1998): 65-68. - [Alternating Hemiplegia of Childhood: Presentation of Two Cases Regarding the Extent of Variability](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-presentation-of-two-cases-regarding-the-extent-of-variability/) - Saltik S, Cokar O, Uslu T, Uluduz D, Dervent A. “Alternating Hemiplegia of Childhood: Presentation of Two Cases Regarding the Extent of Variability.” International Epilepsy Journal 6, no (March 2004): 45-48. - [Intermediate Form between Alternating Hemiplegia of Childhood and Rapid-Onset Dystonia-Parkinsonism](https://ahckids.org/resources/intermediate-form-between-alternating-hemiplegia-of-childhood-and-rapid-onset-dystonia-parkinsonism/) - Sasaki M, Ishii A, Saito Y, Hirose S. “Intermediate Form between Alternating Hemiplegia of Childhood and Rapid-Onset Dystonia-Parkinsonism.” Movement Disorders (September 30, 2013). - [Progressive Brain Atrophy in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/progressive-brain-atrophy-in-alternating-hemiplegia-of-childhood/) - Sasaki M, Ishii A, Yoshiaki S, Hirose S. “Progressive Brain Atrophy in Alternating Hemiplegia of Childhood.” Movement Disorders: Clinical Practice 4, no. 3 (May/June 2017): 406-411. - [Absence of Small-Vessel Abnormalities in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/absence-of-small-vessel-abnormalities-in-alternating-hemiplegia-of-childhood/) - Sasaki M, Matsufuji H, Inui T, et al. “Absence of Small-Vessel Abnormalities in Alternating Hemiplegia of Childhood.” Brain & Development 33, no. 5 (May 2011): 390-393. - [Abnormal Cerebral Glucose Metabolism in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/abnormal-cerebral-glucose-metabolism-in-alternating-hemiplegia-of-childhood/) - Sasaki M, Sakuma H, Fukushmia A, Yamada K, Ohnishi T, Matsuda H. “Abnormal Cerebral Glucose Metabolism in Alternating Hemiplegia of Childhood.” Brain Development 31, no. 1 (January 2009): 20-26. - [Caregiver’s Burden and Psychosocial Issues in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/caregivers-burden-and-psychosocial-issues-in-alternating-hemiplegia-of-childhood-2/) - Save J, Poncelin D, Auvin S. “Caregiver’s Burden and Psychosocial Issues in Alternating Hemiplegia of Childhood.” Eur J Paediatr Neurol. (May 11, 2013). - [ATP1A3-related Epileptic Encephalopathy Responding to Ketogenic Diet](https://ahckids.org/resources/atp1a3-related-epileptic-encephalopathy-responding-to-ketogenic-diet-3/) - Schirinzi T, Graziola F, Cusmai R, Fusco L, Nicita F, Elia M, Travaglini L, Bertini E, Curatolo P, Vigevano F, Capuano A. “ATP1A3-related Epileptic Encephalopathy Responding to Ketogenic Diet.” Brain Dev. 2018 Jan 26. Abstract: https://www.sciencedirect.com/science/article/pii/S0387760418300068?via%3Dihub - [White Matter and Cerebellar Involvement in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/white-matter-and-cerebellar-involvement-in-alternating-hemiplegia-of-childhood/) - Severino M, Pisciotta L, Tortora D, Toselli B, Stagnaro M, Cordani R, Morana G, Zicca A, Kotzeva S, Zanaboni C, Montobbio G, Rossi A, De Grandis E; IBAHC Consortium. “White Matter and Cerebellar Involvement in Alternating Hemiplegia of Childhood.” J Neurol. 2020 Jan 16. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31950366 - [Alternating Hemiplegia of Childhood: A Study of Neuropsychological Functioning](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-a-study-of-neuropsychological-functioning-2/) - Shafer ME, Mayfield JW, McDonald F. “Alternating Hemiplegia of Childhood: A Study of Neuropsychological Functioning.” Applied Neuropsychology 12, no. 1 (2005): 49-56. - [A Boy with Nystagmus, Refractory Dystonia and Apneic Attack Due to Alternating Hemiplegia of Childhood](https://ahckids.org/resources/a-boy-with-nystagmus-refractory-dystonia-and-apneic-attack-due-to-alternating-hemiplegia-of-childhood/) - Shiota N, Shimono M, Tomioka S, et al. “A Boy with Nystagmus, Refractory Dystonia and Apneic Attack Due to Alternating Hemiplegia of Childhood.” Brain and Development 39, no. 4 (July 2007): 285-288. - [Single-photon Emission Computed Tomography Investigations of Alternating Hemiplegia of Childhood](https://ahckids.org/resources/single-photon-emission-computed-tomography-investigations-of-alternating-hemiplegia-of-childhood/) - Siemes H, Cordes M. “Single-photon Emission Computed Tomography Investigations of Alternating Hemiplegia of Childhood.” Developental Medicine & Child Neurology 35, no. 4 (April 1993) 346-350. - [Post-ictal EEG Findings in a Patient Diagnosed with Alternating Hemiplegia of Childhood (AHC)](https://ahckids.org/resources/post-ictal-eeg-findings-in-a-patient-diagnosed-with-alternating-hemiplegia-of-childhood-ahc-2/) - Spina Silva T, Antoniuk S, Bruk I, Crippa, A. “Post-ictal EEG Findings in a Patient Diagnosed with Alternating Hemiplegia of Childhood (AHC).” Journal of the Neurological Sciences 333, Supplement 1 (October 15, 2013): e630. - [Spontaneously Fluctuating Motor Cortex Excitability in Alternating Hemiplegia of Childhood: A Transcranial Magnetic Stimulation Study](https://ahckids.org/resources/spontaneously-fluctuating-motor-cortex-excitability-in-alternating-hemiplegia-of-childhood-a-transcranial-magnetic-stimulation-study/) - Stern WM, Desikan M, Hoad D, Jaffer F, Strigaro G, Sander JW, Rothwell JC, Sisodiya SM. “Spontaneously Fluctuating Motor Cortex Excitability in Alternating Hemiplegia of Childhood: A Transcranial Magnetic Stimulation Study.” PLos ONE 11, no. 3 (March 21, 2016). - [Alternating Hemiplegia of Childhood: Early Characteristics and Evolution of a Neurodevelopmental Syndrome](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-early-characteristics-and-evolution-of-a-neurodevelopmental-syndrome-2/) - Sweney MT, Silver K, Gerard-Blanluet M, Pedespan JM, Renault F, Arzimanoglou A, Schlesinger-Massart M, Lewelt AJ, Reyna SP, Swoboda KJ. “Alternating Hemiplegia of Childhood: Early Characteristics and Evolution of a Neurodevelopmental Syndrome.” Pediatrics 123, no. 3 (March 2009): e534-541. - [A Syndrome of Autosomal Dominate Alternating Hemiplegia: Clinical Presentation Mimicking Intractable Epilepsy: Chromosomal Studies; and Physiologic Investigations](https://ahckids.org/resources/a-syndrome-of-autosomal-dominate-alternating-hemiplegia-clinical-presentation-mimicking-intractable-epilepsy-chromosomal-studies-and-physiologic-investigations/) - Mikati, MA. “A Syndrome of Autosomal Dominate Alternating Hemiplegia: Clinical Presentation Mimicking Intractable Epilepsy: Chromosomal Studies; and Physiologic Investigations.” Neurology 43 (1992): 2251-2257. - [PET Scan Findings in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/pet-scan-findings-in-alternating-hemiplegia-of-childhood/) - Mikati M, Fischman A. “PET Scan Findings in Alternating Hemiplegia of Childhood.” Alternating Hemiplegia of Childhood (1995): 109–114. - [Alternating Hemiplegia of Childhood: Clinical Manifestations and Long-Term Outcome](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-clinical-manifestations-and-long-term-outcome/) - Mikati MA, Kramer U, Zupanc ML, Shanaha RJ. “Alternating Hemiplegia of Childhood: Clinical Manifestations and Long-Term Outcome.” Pediatric Neurology 23, no. 2 (August 2000): 134-141. - [Autosomal Dominant Alternating Hemiplegia of Childhood](https://ahckids.org/resources/autosomal-dominant-alternating-hemiplegia-of-childhood/) - Mikati M, O’Tuama L, Dangond F. “Autosomal Dominant Alternating Hemiplegia of Childhood.” Alternating Hemiplegia of Childhood (1995): 125–134. - [Characteristic Asymmetric Abnormal Eye Movement and Dystonic Posture as the First Symptoms of Alternating Hemiplegia of Childhood](https://ahckids.org/resources/characteristic-asymmetric-abnormal-eye-movement-and-dystonic-posture-as-the-first-symptoms-of-alternating-hemiplegia-of-childhood/) - Motoki T, Sasaki M, Ishii A, Hirose S. “Characteristic Asymmetric Abnormal Eye Movement and Dystonic Posture as the First Symptoms of Alternating Hemiplegia of Childhood.” No To Hattatsu (March 2016). (Japanese) - [Neuropsychological Deficits in Alternating Hemiplegia of Childhood: a Case Study](https://ahckids.org/resources/neuropsychological-deficits-in-alternating-hemiplegia-of-childhood-a-case-study-2/) - Muriel V, Garcia-Molina A, Aparicio-Lopez C, Ensenat A, Roig-Rovira T. “Neuropsychological Deficits in Alternating Hemiplegia of Childhood: a Case Study.” Revista de Neurologica (July 1, 2015) (In Spanish). Montirosso R, Ceppi E, D’aloisio C, Zucca C, Borgatti R. “International Classification of Functioning, Disability and Health in Subjects with Alternating Hemiplegia of Childhood.” Disability & Rehabilitation - [Heart Rate Variability in a Patient with Alternating Hemiplegia](https://ahckids.org/resources/heart-rate-variability-in-a-patient-with-alternating-hemiplegia-2/) - Nakashima T, Yasuda K, Kobayashi M, Wada H, Ishii A, Hirose S. “Heart Rate Variability in a Patient with Alternating Hemiplegia.” Intractable Rare Diseases Research. 2019 May; 8(2): 134-137. Fulltext:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557234/ - [Bath-Induced Paroxysmal Disorders in Infancy](https://ahckids.org/resources/bath-induced-paroxysmal-disorders-in-infancy/) - Nechay A, Stephenson JB. “Bath-Induced Paroxysmal Disorders in Infancy.” European Journal of Paediatric Neurology 13, no. 3 (May 2009): 203-208. - [Exercise Induced Steroid Dependent Dystonia, Ataxia, and Alternating Hemiplegia Associated with Epilepsy](https://ahckids.org/resources/exercise-induced-steroid-dependent-dystonia-ataxia-and-alternating-hemiplegia-associated-with-epilepsy/) - Neville B, Besag F, Marsden C. “Exercise Induced Steroid Dependent Dystonia, Ataxia, and Alternating Hemiplegia Associated with Epilepsy.” Journal of Neurology, Neurosurgery, and Psychiatry 65, no. 2 (August 1998): 241-244. - [The Treatment and Management of Alternating Hemiplegia of Childhood](https://ahckids.org/resources/the-treatment-and-management-of-alternating-hemiplegia-of-childhood-2/) - Neville BG, Ninan M. “The Treatment and Management of Alternating Hemiplegia of Childhood.” Developmental Medicine and Child Neurolog 49, no.10 (October 2007): 777-80. - [Alternating Hemiplegia of Childhood: A Cross-sectional Study](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-a-cross-sectional-study/) - Nevsimalova S, Dittirch J, Havlova M, Tauberova A, Korsova B, Hajek M, Masopust J, Michalova K. “Alternating Hemiplegia of Childhood: A Cross-sectional Study.” Brain & Development 16 (1994): 190-94. - [Alternating Hemiplegia of Childhood with Novel Features](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-with-novel-features/) - Padmanabha H, Goswami JN, Sahu JK, Swaboda KJ, Singhi P. “Alternating Hemiplegia of Childhood with Novel Features.” Indian Journal of Pediatrics 84, no. 6 (June 2017): 473-474. - [Alternating Hemiplegia of Childhood: The Gap Between Paroxysmal Manifestations and Non-Paroxysmal Characteristics](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-the-gap-between-paroxysmal-manifestations-and-non-paroxysmal-characteristics/) - Panagiotakaki E. “Alternating Hemiplegia of Childhood: The Gap Between Paroxysmal Manifestations and Non-Paroxysmal Characteristics.” Developmental Medicine & Child Neurology. 2019 May; 61(5): 506. Fulltext: https://onlinelibrary.wiley.com/doi/full/10.1111/dmcn.14137 - [Evidence of a Non-Progressive Course of Alternating Hemiplegia of Childhood: Study of a Large Cohort of Children and Adults](https://ahckids.org/resources/evidence-of-a-non-progressive-course-of-alternating-hemiplegia-of-childhood-study-of-a-large-cohort-of-children-and-adults/) - Panagiotakaki E, Gobbi G, Neville B, et al. “Evidence of a Non-Progressive Course of Alternating Hemiplegia of Childhood: Study of a Large Cohort of Children and Adults.” Brain, a Journal of Neurology 133 Pt. 12 (December 2010): 3598-3610. - [Caesarean Section Under General Anaesthetic in a Woman with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/caesarean-section-under-general-anaesthetic-in-a-woman-with-alternating-hemiplegia-of-childhood/) - Parris-Piper T. “Caesarean Section Under General Anaesthetic in a Woman with Alternating Hemiplegia of Childhood.” International Journal of Obstetric Anesthesia 11, no. 4 (October 2002): 317-320. - [Alternating Hemiplegia of Childhood: neurological comorbidities and intrafamilial variability](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-neurological-comorbidities-and-intrafamilial-variability/) - Pavone P, Pappalardo XG, Mustafa N, Cho SY, Jin DK, Incorpora G, Falsaperla R, Marino SD, Corsello G, Parano E, Ruggieri M. Alternating Hemiplegia of Childhood: neurological comorbidities and intrafamilial variability. Ital J Pediatr. 2022 Feb 17;48(1):29. https://ijponline.biomedcentral.com/articles/10.1186/s13052-021-01194-2 - [EEG Findings during Paroxysmal Hemiplegia in a Patient with GLUT1-deficiency](https://ahckids.org/resources/eeg-findings-during-paroxysmal-hemiplegia-in-a-patient-with-glut1-deficiency/) - Pellegrin S, Cantalupo G, Opri R, Dalla Bernardina B, Darra F. “EEG Findings during Paroxysmal Hemiplegia in a Patient with GLUT1-deficiency.” European Journal of Paediatric Neurology 21, no. 3 (May 2017): 580-582. - [Non-Stationary Outcome of Alternating Hemiplegia of Childhood into Adulthood](https://ahckids.org/resources/non-stationary-outcome-of-alternating-hemiplegia-of-childhood-into-adulthood/) - Perulli M, Poole J, Di Lazzaro G, D'Ambrosio S, Silvennoinen K, Zagaglia S, Jiménez-Jiménez D, Battaglia D, Sisodiya SM, Balestrini S. Non-Stationary Outcome of Alternating Hemiplegia of Childhood into Adulthood. Mov Disord Clin Pract. 2021 Dec 29;9(2):206-211. Fulltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810436/ - [Alpha(11C) Methyl-L-typtophan Positron Emission Tomography in Patients with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/alpha11c-methyl-l-typtophan-positron-emission-tomography-in-patients-with-alternating-hemiplegia-of-childhood/) - Pfund Z, Chugani D, Muzik O, Behen M, Lee J, Chakraborty P. “Alpha(11C) Methyl-L-typtophan Positron Emission Tomography in Patients with Alternating Hemiplegia of Childhood.” Journal of Child Neurology 17 no. 4 (April 2002): 253-260. - [Alternating Hemiplegia of Childhood: Pharmacological Treatment of 30 Italian Patients](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-pharmacological-treatment-of-30-italian-patients/) - Pisciotta L, Gherzi M, Stagnaro M, et al. “Alternating Hemiplegia of Childhood: Pharmacological Treatment of 30 Italian Patients.” Brain & Development 39, no. 6 (June 2017): 521-528. - [Alternating Hemiplegia of Childhood in Spanish Population, Study of a Series of 17 Patients](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-spanish-population-study-of-a-series-of-17-patients/) - Fons C, Campistol J, Narbona J, Velazquez R, Eiris J, Garcia Penas J. “Alternating Hemiplegia of Childhood in Spanish Population, Study of a Series of 17 Patients.” Med Clin (Barc) 13 (April 26, 2008): 577-579. (In Spanish) - [Alternating Hemiplegia of Childhood: New Diagnostic Options](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-new-diagnostic-options/) - Gergont A, Kacinski M. “Alternating Hemiplegia of Childhood: New Diagnostic Options.” Neurol Neurochir Pol. 48, no.2 (February 2015). - [Alternating Hemiplegia: Italian White Book for Understanding and Managing this Rare Disease](https://ahckids.org/resources/alternating-hemiplegia-italian-white-book-for-understanding-and-managing-this-rare-disease/) - Granata T, Vigevano F. Alternating Hemiplegia: Italian White Book for Understanding and Managing this Rare Disease. Associazione Italiana per la Sindrome di Emiplegia Alternante. Italy, 2007. - [Recognizable Facial Features in Patients with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/recognizable-facial-features-in-patients-with-alternating-hemiplegia-of-childhood/) - Gurrieri F, Tiziano FD, Zampino G, Neri G. “Recognizable Facial Features in Patients with Alternating Hemiplegia of Childhood.” American Journal of Medical Genetics: Part A. 170, no. 10 (October 2016): 2698-2705. - [Alternating Hemiplegia of Childhood in Denmark: Clinical Manifestations and ATP1A3 Mutation Status](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-denmark-clinical-manifestations-and-atp1a3-mutation-status-3/) - Hoei-Hansen C, Dali C, Lyngbye T, Duno M, Uldall P. “Alternating Hemiplegia of Childhood in Denmark: Clinical Manifestations and ATP1A3 Mutation Status.” European Journal of Paediatric Neurology (September 25, 2013). - [Knock-in Mouse Model of Alternating Hemiplegia of Childhood: Behavioral and Electrophysiologic Characterization](https://ahckids.org/resources/knock-in-mouse-model-of-alternating-hemiplegia-of-childhood-behavioral-and-electrophysiologic-characterization-2/) - Hunanyan Aresn, Fainberg N, Linabarger M, Arehart E, Leonard A, Adil S, Mikati M. “Knock-in Mouse Model of Alternating Hemiplegia of Childhood: Behavioral and Electrophysiologic Characterization.” Epilepsia (December 19, 2014). - [Neuronatal Onset of Bath-Induced Alternating Hemiplegia of Childhood](https://ahckids.org/resources/neuronatal-onset-of-bath-induced-alternating-hemiplegia-of-childhood/) - Incorpora G, Pavone P, Cocuzza M, Privitera M, Pavone L, Ruggieri M. “Neuronatal Onset of Bath-Induced Alternating Hemiplegia of Childhood.” European Journal of Paediatric Neurology 14. no. 2 (May 2010): 192-193. - [An 11-Year Follow-up Study of Neonatal-Onset, Bath-induced Alternating Hemiplegia of Childhood in Twins](https://ahckids.org/resources/an-11-year-follow-up-study-of-neonatal-onset-bath-induced-alternating-hemiplegia-of-childhood-in-twins/) - Incorpora G, Pavone P, Polizzi A, et al. “An 11-Year Follow-up Study of Neonatal-Onset, Bath-induced Alternating Hemiplegia of Childhood in Twins.” Journal of Child Neurology 27, no. 5(May 2012): 657-662. - [Cardiac Features in Adults with Alternating Hemiplegia](https://ahckids.org/resources/cardiac-features-in-adults-with-alternating-hemiplegia/) - Jaffer F, Avbersek A, Kaski J, Parton M, Houlden H, Hanna M, Cross JH, Sisodiya S. “Cardiac Features in Adults with Alternating Hemiplegia.” Journ of Neurology and Neurosurgery Psychaitry (2014): 85. - [Faulty Cardiac Repolarization Reserve in Alternating Hemiplegia of Childhood Broadens the Phenotype](https://ahckids.org/resources/faulty-cardiac-repolarization-reserve-in-alternating-hemiplegia-of-childhood-broadens-the-phenotype/) - Jaffer F, Avbersek A, Vavassori R, Fons C, Campistol J, Stagnaro M, De Grandis E, Veneselli E, Rosewich H, Gianotta M, Zucca C, Ragona F, Granata T, Nardocci N, Mikati M, Helseth AR, Boelman C, Minassian BA, Johns S, Garry SI, Scheffer IE, Gourfinkel-An I, Carrilho I, Aylett SE, Parton M, Hanna MG, Houlden H, - [Polysomnography Findings and Sleep Disorders in Children With Alternating Hemiplegia of Childhood](https://ahckids.org/resources/polysomnography-findings-and-sleep-disorders-in-children-with-alternating-hemiplegia-of-childhood/) - Kansagra S, Ghusayni R, Kherallah B, Gunduz T, McLean M, Prange L, Kravitz RM, Mikati MA. “Polysomnography Findings and Sleep Disorders in Children With Alternating Hemiplegia of Childhood.” J Clin Sleep Med. 2019 Jan 15; 15(1): 65-70. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30621840 - [Alternating Hemiplegia of Childhood in Half-sisters](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-half-sisters/) - Kansagra, S, Mikati, Mohamad, Vigevano, F. “Alternating Hemiplegia of Childhood.” Handbook of Clinical Neurology 112 (2013): 821-826. - [Alternating Hemiplegia of Childhood in Half-sisters](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-half-sisters-2/) - Kramer U, Nevo Y, Margalit D, et al. “Alternating Hemiplegia of Childhood in Half-sisters.” Journal of Child Neurology 15, no. 2 (2000): 128–30. - [Flunarizine Versus Topiramate for Chronic Migraine Prophylaxis: A Randomized Trial](https://ahckids.org/resources/flunarizine-versus-topiramate-for-chronic-migraine-prophylaxis-a-randomized-trial-2/) - Lai KL, Niddam DM, Fuh JL, Chen SP, Wang YF, Chen WT, Wu JC, Wang SJ. “Flunarizine Versus Topiramate for Chronic Migraine Prophylaxis: A Randomized Trial.” Acta Neurologica Scandinavica (June 16, 2016). - [Diagnosis of Alternating Hemiplegia of Childhood](https://ahckids.org/resources/diagnosis-of-alternating-hemiplegia-of-childhood/) - Luo R. “Diagnosis of Alternating Hemiplegia of Childhood,” Chinese Journal of Contemporary Pediatrics 19, no.9 (September 4, 2017): 959-960. (in Chinese) Maas R, Kamsteeg E, Mangano S, Lopez M, Nicolai J, Silver K, Fernandez-Alvarez E, Willemsen M. “Benign Nocturnal Alternating Hemiplegia of Childhood: A Clinical and Nomenclatural Reappraisal.” European Jourrnal of Paediactric Neurology. 2018 Nov; - [Alternating Hemiplegia with Ipsilateral Supranuclear Facial Palsy and Abducens Nerve Palsy Caused by Pontine Infarction](https://ahckids.org/resources/alternating-hemiplegia-with-ipsilateral-supranuclear-facial-palsy-and-abducens-nerve-palsy-caused-by-pontine-infarction/) - Maeshima S, Tsunoda T, Okamoto S, Ozeki Y, Sonoda S. “Alternating Hemiplegia with Ipsilateral Supranuclear Facial Palsy and Abducens Nerve Palsy Caused by Pontine Infarction.” Internal Medicine 55, no. 15 (2016): 2073-2075. - [Benign Nocturnal Alternating Hemiplegia of Childhood: A New Case with Unusual Findings](https://ahckids.org/resources/benign-nocturnal-alternating-hemiplegia-of-childhood-a-new-case-with-unusual-findings/) - Mangano S, Fontana A, Spitaleri C, Mangano GR. “Benign Nocturnal Alternating Hemiplegia of Childhood: A New Case with Unusual Findings.” Brain Dev. 36, no. 5 (May 2014): 408-410. - [General Anesthesia for a Patient with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/general-anesthesia-for-a-patient-with-alternating-hemiplegia-of-childhood/) - Mehrotra R. “General Anesthesia for a Patient with Alternating Hemiplegia of Childhood.” Canadian Journal of Anesthesia 52, no. 10 (December 2005): 1103-1104. - [Alternating Hemiplegia and Cardiac Dysrhythmia](https://ahckids.org/resources/alternating-hemiplegia-and-cardiac-dysrhythmia/) - Millichap, JG. “Alternating Hemiplegia and Cardiac Dysrhythmia.” Pediatric Neurology Briefs (September 2015). - [Alternating Hemiplegia of Childhood](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-3/) - Mikati, MA. “Alternating Hemiplegia of Childhood.” Pediatric Neurology 21, no. 4 (October 1999): 764-. - [Management of Alternating Hemiplegia of Childhood: A Review](https://ahckids.org/resources/management-of-alternating-hemiplegia-of-childhood-a-review/) - Samanta D. “Management of Alternating Hemiplegia of Childhood: A Review.” Pediatr Neurol. 2019 Nov 1. 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Abstract: https://www.sciencedirect.com/science/article/pii/S0387760418300068?via%3Dihub - [Alternating Hemiplegia of Childhood: First South African Case Report and Verapamil as a Possible Treatment Option](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-first-south-african-case-report-and-verapamil-as-a-possible-treatment-option/) - Van Hillegondsberg LS, Michaelis IA. “Alternating Hemiplegia of Childhood: First South African Case Report and Verapamil as a Possible Treatment Option.” S Afr Med J. 2019 Feb; 109(3): 152-153. 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84;(12): 957-958. - [Flunarizine rescues reduced Lifespan in CLN3 Triple Knock-out Caenorhabditis Elegans Model of Batten Disease](https://ahckids.org/resources/flunarizine-rescues-reduced-lifespan-in-cln3-triple-knock-out-caenorhabditis-elegans-model-of-batten-disease/) - Kwon YJ, Falk MJ, Bennett MJ. “Flunarizine rescues reduced Lifespan in CLN3 Triple Knock-out Caenorhabditis Elegans Model of Batten Disease.” Journal of Inherited Metabolic Disease (October 20, 2016). - [Flunarizine Versus Topiramate for Chronic Migraine Prophylaxis: A Randomized Trial](https://ahckids.org/resources/flunarizine-versus-topiramate-for-chronic-migraine-prophylaxis-a-randomized-trial/) - Lai KL, Niddam DM, Fuh JL, Chen SP, Wang YF, Chen WT, Wu JC, Wang SJ. “Flunarizine Versus Topiramate for Chronic Migraine Prophylaxis: A Randomized Trial.” Acta Neurologica Scandinavica (June 16, 2016). - [Safety and Efficacy of Flunarizine in Childhood Migraine: 11 Years’ Experience, with Emphasis on its Effect in Hemiplegic Migraine](https://ahckids.org/resources/safety-and-efficacy-of-flunarizine-in-childhood-migraine-11-years-experience-with-emphasis-on-its-effect-in-hemiplegic-migraine/) - Mohamed BP, Goadsby J, Prabhakar P. “Safety and Efficacy of Flunarizine in Childhood Migraine: 11 Years’ Experience, with Emphasis on its Effect in Hemiplegic Migraine.” Developmental Medicine & Child Neurology (January 23, 2012). - [Flunarizine for Treatment of Partial Seizures: Results of a Concentration-Controlled Trial](https://ahckids.org/resources/flunarizine-for-treatment-of-partial-seizures-results-of-a-concentration-controlled-trial/) - Pledger GW. “Flunarizine for Treatment of Partial Seizures: Results of a Concentration-Controlled Trial.” Neurology 44, no.10 (1994): 1830-1836. - [Genotype-Phenotype Correlations in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/genotype-phenotype-correlations-in-alternating-hemiplegia-of-childhood-2/) - Sasaki M, Ishii A, Saito Y, Morisada N, et al. “Genotype-Phenotype Correlations in Alternating Hemiplegia of Childhood.” Neurology (January 15, 2014). - [Long-term Effect of Flunarizine on Patients with Alternating Hemiplegia of Childhood in Japan](https://ahckids.org/resources/long-term-effect-of-flunarizine-on-patients-with-alternating-hemiplegia-of-childhood-in-japan-2/) - Sasaki M, Sakuragawa N, Osawa M. “Long-term Effect of Flunarizine on Patients with Alternating Hemiplegia of Childhood in Japan.” Brain Development 23, no. 5 (August 2001): 303-305. - [Antidepressant-Like Activity of Flunarizine in Modified Tail Suspension Test in Rats](https://ahckids.org/resources/antidepressant-like-activity-of-flunarizine-in-modified-tail-suspension-test-in-rats/) - Shinde V, Yegnanarayan R, Shah P, Gupta A, Pophale P. “Antidepressant-Like Activity of Flunarizine in Modified Tail Suspension Test in Rats.” North American Journal of Medical Sciences 7, no. 3 (March 2015): 100-3. - [Rectal Chloral Hydrate for Alternating Hemiplegia of Childhood](https://ahckids.org/resources/rectal-chloral-hydrate-for-alternating-hemiplegia-of-childhood/) - Siemes, H. “Rectal Chloral Hydrate for Alternating Hemiplegia of Childhood.” Developmental Medicine and Child Neurology 32, no. 10 (October 1990): 931-. - [Allelic Variations of Glut-1 Deficiency Syndrome: the Chinese Experience](https://ahckids.org/resources/allelic-variations-of-glut-1-deficiency-syndrome-the-chinese-experience/) - Liu Y, Bao X, Wang D, et al. “Allelic Variations of Glut-1 Deficiency Syndrome: the Chinese Experience.” Pediatric Neurology47, no. 1 (July 2012): 30-34. Ozelius, L. “Clinical Spectrum of Disease Associated with ATP1A3 Mutations.” Lancet Neurology 11, no. 9 (September 2012): 741-743. - [Alternating Hemiplegia and Epilepsia Partialis Continua: a New Phenotype for a Novel Compound TBC1D24 Mutation](https://ahckids.org/resources/alternating-hemiplegia-and-epilepsia-partialis-continua-a-new-phenotype-for-a-novel-compound-tbc1d24-mutation/) - Ragona F, Castellotti B, Salis B, Magri S and others. “Alternating Hemiplegia and Epilepsia Partialis Continua: a New Phenotype for a Novel Compound TBC1D24 Mutation.” Seizure (March 6, 2017). - [A Novel ATP1A3 Mutation with Unique Clinical Presentation](https://ahckids.org/resources/a-novel-atp1a3-mutation-with-unique-clinical-presentation-2/) - Rosewich H. Baethmann M, Ohlenbush A, Gartner J, Brockmann K. “A Novel ATP1A3 Mutation with Unique Clinical Presentation.” J Neurol Sci. 341 (June 15, 2014). - [The Expanding Clinical and Genetic Spectrum of ATP1A3-Related Disorders](https://ahckids.org/resources/the-expanding-clinical-and-genetic-spectrum-of-atp1a3-related-disorders-2/) - Rosewich H, Ohlenbusch A, Huppke P, Schlotawa L, Baethmann M, Carriho L, Fiori S, Lourenco CM, Sawyer S, Steinfeld R, Gartner J, Brockmann K. “The Expanding Clinical and Genetic Spectrum of ATP1A3-Related Disorders.” Neurology 18, no. 82 (March 18, 2014): 945-955. - [Heterozygous De-Novo Mutations in ATP1A3 in Patients with Alternating Hemiplegia of Childhood: A Whole-Exome Sequencing Gene-Identification Study](https://ahckids.org/resources/heterozygous-de-novo-mutations-in-atp1a3-in-patients-with-alternating-hemiplegia-of-childhood-a-whole-exome-sequencing-gene-identification-study-3/) - Rosewich H, Thiele H, Ohlenbusch A, et al. “Heterozygous De-Novo Mutations in ATP1A3 in Patients with Alternating Hemiplegia of Childhood: A Whole-Exome Sequencing Gene-Identification Study.” Lancet Neurology 11, no.9 (September 2012): 764-73. - [Phenotypic Overlap of Alternating Hemiplegia of Childhood and CAPOS Syndrome](https://ahckids.org/resources/phenotypic-overlap-of-alternating-hemiplegia-of-childhood-and-capos-syndrome/) - Rosewich H, Weise D, Ohlenbusch A, Gartner J, Brockmann K. “Phenotypic Overlap of Alternating Hemiplegia of Childhood and CAPOS Syndrome.” Neurology (August 26, 2014). - [Glut1 Deficiency and Alternating Hemiplegia of Childhood](https://ahckids.org/resources/glut1-deficiency-and-alternating-hemiplegia-of-childhood/) - Rotstein M, Doran J, Yang, H, Ullner PM, Engelstad K, DeVivo DC. “Glut1 Deficiency and Alternating Hemiplegia of Childhood.” Neurology 73, no.23 (December 8, 2009): 2042-2044. - [Genotype-Phenotype Correlations in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/genotype-phenotype-correlations-in-alternating-hemiplegia-of-childhood/) - Sasaki M, Ishii A, Saito Y, Morisada N, et al. “Genotype-Phenotype Correlations in Alternating Hemiplegia of Childhood.” Neurology 82, no. 6 (February 11, 2014): 482-490. - [Homozygous TANGO2 Single Nucleotide Variants Presenting with Additional Manifestations Resembling Alternating Hemiplegia of Childhood-Expanding the Phenotype of a Recently Reported Condition](https://ahckids.org/resources/homozygous-tango2-single-nucleotide-variants-presenting-with-additional-manifestations-resembling-alternating-hemiplegia-of-childhood-expanding-the-phenotype-of-a-recently-reported-condition/) - Sen K, Hicks MA, Huq AHM, Agarwal R. “Homozygous TANGO2 Single Nucleotide Variants Presenting with Additional Manifestations Resembling Alternating Hemiplegia of Childhood-Expanding the Phenotype of a Recently Reported Condition.” Neuropediatrics. 2019 Apr; 50(2): 122-125. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30650451 - [Targeted Exome Analysis Identifies the Genetic Basis of Disease in over 50% of Patients with a Wide Range of Ataxia-related Phenotypes](https://ahckids.org/resources/targeted-exome-analysis-identifies-the-genetic-basis-of-disease-in-over-50-of-patients-with-a-wide-range-of-ataxia-related-phenotypes/) - Sun M, Johnson AK, Nelakuditi V, Guidugli L, Fischer D, Arndt K, Ma L, Sandford E, Shakkottai V, Boycott K, Chardon JW, Li Z, Del Gaudio D, Burmeister M, Gomez CM, Waggoner DJ, Das S. “Targeted Exome Analysis Identifies the Genetic Basis of Disease in over 50% of Patients with a Wide Range of Ataxia-related - [The Expanding Spectrum of Neurological Phenotypes in Children with ATP1A3 Mutations, Alternating Hemiplegia of Childhood, Rapid-onset Dystonia-Parkinsonism, CAPOS and Beyond](https://ahckids.org/resources/the-expanding-spectrum-of-neurological-phenotypes-in-children-with-atp1a3-mutations-alternating-hemiplegia-of-childhood-rapid-onset-dystonia-parkinsonism-capos-and-beyond-3/) - Sweney M, Newcomb T, Swoboda K. “The Expanding Spectrum of Neurological Phenotypes in Children with ATP1A3 Mutations, Alternating Hemiplegia of Childhood, Rapid-onset Dystonia-Parkinsonism, CAPOS and Beyond.” Pediatric Neurology (January 2015): 56-64. - [Genome-Wide Screen for Modifiers of Na+/K+ATPase Alleles Identifies Critical Genetic Loci](https://ahckids.org/resources/genome-wide-screen-for-modifiers-of-na-katpase-alleles-identifies-critical-genetic-loci/) - Talsma A, Chaves J, LaMonaca A, Wieczorek, Palladino M. “Genome-Wide Screen for Modifiers of Na+/K+ATPase Alleles Identifies Critical Genetic Loci.” Mol Brain (December 5, 2014). - [Single K ATP Channel Opening in Response to Action Potential Firing in Mouse Dentate Granule Neurons](https://ahckids.org/resources/single-k-atp-channel-opening-in-response-to-action-potential-firing-in-mouse-dentate-granule-neurons/) - Tanner GR, Lutas A, Martinez-Francois JR, Yellen G. “Single K ATP Channel Opening in Response to Action Potential Firing in Mouse Dentate Granule Neurons.” Journal of Neuroscience 31, no.23 (June 8, 2011). - [Alternating Hemiplegia of Childhood with a De Novo Mutation in ATP1A3 and Changes in SLC2A1 Responsive to Ketogenic Diet](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-with-a-de-novo-mutation-in-atp1a3-and-changes-in-slc2a1-responsive-to-ketogenic-diet/) - Ulate-Campos A, Fons C, Arthuc R, Castejon E, Martorell L, Ozelius L, Pascual J, Campistol J. “Alternating Hemiplegia of Childhood with a De Novo Mutation in ATP1A3 and Changes in SLC2A1 Responsive to Ketogenic Diet.” Pediatr Neurol (April 2014): 377-379. - [Clinical and Genetic Analysis in Alternating Hemiplegia of Childhood: Ten New Patients from Southern Europe](https://ahckids.org/resources/clinical-and-genetic-analysis-in-alternating-hemiplegia-of-childhood-ten-new-patients-from-southern-europe/) - Vila-Pueyo M, Pons R, Raspall-Chaure M, Marcė-Grau A, Carreńno O, Sintas C, Cormand B, Pineda-Marfá M, Macaya A. “Clinical and Genetic Analysis in Alternating Hemiplegia of Childhood: Ten New Patients from Southern Europe.” J Neurol Sci. 344, no.1–2 (2014): 37–42. - [Name](https://ahckids.org/resources/name/) - Viollet L, Glusman G, Murphy KJ, Newcomb TM, Reyna SP, Sweney M, Nelso B, Andermann F, Andermann E, Ascadi G, Barbano RL, Brown C, Brunkow ME, Chugani HT, Cheyette SR, Collins A, DeBrosse Sd, Galas D, Friedman J, Hood L, Huff C, Jorde - [Alternating Hemiplegia of Childhood: Retrospective Genetic Study and Genotype-Phenotype Correlations in 187 Subjects from the US AHCF Registry](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-retrospective-genetic-study-and-genotype-phenotype-correlations-in-187-subjects-from-the-us-ahcf-registry/) - LB, King MD, LaSalle B, leventer RJ, Lewelt AJ, Massart MB, Merida MR 2nd, Ptacke LJ, Roach JC, Rust RS, Renault F, Stanger TD, Sotero de Menezes MA, Tennyson R, Uldall P, Zhang Y, Zupanc M, Xin W, Silver K, Swoboda KJ. “Alternating Hemiplegia of Childhood: Retrospective Genetic Study and Genotype-Phenotype Correlations in 187 Subjects - [Absence of Mutation in the SLC2A1 Gene in a Cohort of Patients with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/absence-of-mutation-in-the-slc2a1-gene-in-a-cohort-of-patients-with-alternating-hemiplegia-of-childhood/) - Vuillaumier-Barrot, S., Panagiotakaki, E., Le Bizec, C., and others. “Absence of Mutation in the SLC2A1 Gene in a Cohort of Patients with Alternating Hemiplegia of Childhood.” Neuropediatrics 41, no.6 (December 2010): 267-269. - [A Novel SLC2A1 Mutation Linking Hemiplegic Migraine with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/a-novel-slc2a1-mutation-linking-hemiplegic-migraine-with-alternating-hemiplegia-of-childhood/) - Weller CM, Leen WG, Neville BG, Duncan JS, Vries BD, Geilenkirchen MA, Haan J, Kamsteeg EJ, Ferrari MD, Maagdenberg AM, Willemsen MA, Scheffer H, Terwindt GM. “A Novel SLC2A1 Mutation Linking Hemiplegic Migraine with Alternating Hemiplegia of Childhood.” Cephalalgia (May 13, 2014). - [Alternating Hemiplegia of Childhood as a New Presentation of Adenylate Cyclase 5-Mutation-Associated Disease: A Report of Two Cases](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-as-a-new-presentation-of-adenylate-cyclase-5-mutation-associated-disease-a-report-of-two-cases/) - Westenberger A, Max C, Brüggemann N, Domingo A, Grütz K, Pawlack H, Weissbach A, Kühn AA, Spiegler J, Lang AE, Sperner J, Fung VS, Schallner J, Gillessen-Kaesbach G, Münchau A, Klein C. “Alternating Hemiplegia of Childhood as a New Presentation of Adenylate Cyclase 5-Mutation-Associated Disease: A Report of Two Cases.” Journal of Pediatrics (February 2017): - [ATP1A3 Mutations](https://ahckids.org/resources/atp1a3-mutations/) - Brashear A, Ozelius L, Sweadner K. “ATP1A3 Mutations.” Neurology (February 11, 2014). - [Episodic Movement Disorders: From Phenotype to Genotype and Back](https://ahckids.org/resources/episodic-movement-disorders-from-phenotype-to-genotype-and-back/) - Brockmann, K. “Episodic Movement Disorders: From Phenotype to Genotype and Back.” Curr Neurol Neurosci Rep. (October 13, 2013). - [Alternating Hemiplegia of Childhood in a Child Harboring a Novel TBC1D24 Mutation: Case Report and Literature Review](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-a-child-harboring-a-novel-tbc1d24-mutation-case-report-and-literature-review/) - Cordani R, Pisciotta L, Mancardi MM, Stagnaro M, Prato G, Giacomini T, Morana G, Walsh P, Ghia T, Nobili L, De Grandis E. Alternating Hemiplegia of Childhood in a Child Harboring a Novel TBC1D24 Mutation: Case Report and Literature Review. Neuropediatrics. 2022 Feb;53(1):69-74. Fulltext: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0041-1739132 - [Functional Studies and Proteomics in Platelets and Fibroblasts Reveal a Lysosomal Defect with Increased Cathepsin-dependent Apoptosis in ATP1A3 Defective Alternating Hemiplegia of Childhood](https://ahckids.org/resources/functional-studies-and-proteomics-in-platelets-and-fibroblasts-reveal-a-lysosomal-defect-with-increased-cathepsin-dependent-apoptosis-in-atp1a3-defective-alternating-hemiplegia-of-childhood-2/) - Di Michele M, Goubau C, Waelkens E, Thys C, De Vos R, Overbergh L, Schyns T, Buyse G, Casaer P, Van Geet C, Freson K. “Functional Studies and Proteomics in Platelets and Fibroblasts Reveal a Lysosomal Defect with Increased Cathepsin-dependent Apoptosis in ATP1A3 Defective Alternating Hemiplegia of Childhood.” Journal of Proteomics (May 13, 2013). - [Alternating Hemiplegia of Childhood: No Mutations in the Glutamate Transporter EAAT1](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-no-mutations-in-the-glutamate-transporter-eaat1/) - De Vries B, Haan J, Stam AH, Vanmolkot KR, Stoink H, Laan LA, Gill DS, Pascual J, Frants RR, van den Maagdenberg AM, Ferrari MD. “Alternating Hemiplegia of Childhood: No Mutations in the Glutamate Transporter EAAT1.” Neuropediatrics (October 2006): 302-304. 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No abstract. - [Distinct Neurological Disorders with ATP1A3 Mutations](https://ahckids.org/resources/distinct-neurological-disorders-with-atp1a3-mutations-2/) - Heinzen EL, Arzimanoglou A, Brashear A, Clapcote SJ, Gurrieri F, Goldstein DB, Johannesson SH, Mikati MA, Neville B, Nicole S, Ozelius LJ, Poulsen H, Schyns T, Sweadner KJ, van den Maagdenberg A, Vilsen B, ATP1A3 Working Group. “Distinct Neurological Disorders with ATP1A3 Mutations.” Lancet Neurol. 13, no. 5 (May 2014): 503-14. - [De Novo Mutations in ATP1A3 Cause Alternating Hemiplegia of Childhood](https://ahckids.org/resources/de-novo-mutations-in-atp1a3-cause-alternating-hemiplegia-of-childhood-3/) - Heinzen E, Swoboda K, Hitomi Y, et al. “De Novo Mutations in ATP1A3 Cause Alternating Hemiplegia of Childhood.” Nature Genetics 44, no.9 (September 2012): 1030-1034. - [Alternating Hemiplegia of Childhood in Denmark: Clinical Manifestations and ATP1A3 Mutation Status](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-in-denmark-clinical-manifestations-and-atp1a3-mutation-status-2/) - Hoei-Hansen CE, Dali C, Lyngbye TJ, Duno M, Uldall P. “Alternating Hemiplegia of Childhood in Denmark: Clinical Manifestations and ATP1A3 Mutation Status.” European Journal of Paediatric Neurology (September 25, 2013). - [Mosaicism in ATP1A3-Related Disorders: Not Just a Theoretical Risk](https://ahckids.org/resources/mosaicism-in-atp1a3-related-disorders-not-just-a-theoretical-risk-2/) - Hully M, Ropars J, Hubert L, Boddaert N, Rio M, et al. “Mosaicism in ATP1A3-Related Disorders: Not Just a Theoretical Risk.” Neurogenetics (October 10, 2016). - [Enhanced Inhibitory Neurotransmission in the Cerebellar Cortex of the Atp1a3-deficient Heterozygous Mice](https://ahckids.org/resources/enhanced-inhibitory-neurotransmission-in-the-cerebellar-cortex-of-the-atp1a3-deficient-heterozygous-mice/) - Ikeda K, et al. “Enhanced Inhibitory Neurotransmission in the Cerebellar Cortex of the Atp1a3-deficient Heterozygous Mice.” J Physiol. 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Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30392204 - [ATP1A3-related Epilepsy: Report of Seven Cases and Literature-based Analysis of Treatment Response](https://ahckids.org/resources/atp1a3-related-epilepsy-report-of-seven-cases-and-literature-based-analysis-of-treatment-response/) - Gasser M, Boonsimma P, Netbaramee W, Wechapinan T, Srichomthomg C, Ittiwut C, Krenn M, Zimprich F, et al. “ATP1A3-related Epilepsy: Report of Seven Cases and Literature-based Analysis of Treatment Response.” J Clin Neurosci. 2020 Jan 17. 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Fulltext: http://n.neurology.org/content/91/1/47.long - [Alternating Hemiplegia of Childhood: ATP1A3 Gene Analysis in 16 Patients](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-atp1a3-gene-analysis-in-16-patients/) - Ulate-Campos A, Fons C, Campistol J, Martorell L, Cancho-Cadela R, Eiris J, Lopez-Laso E, Pineda M, Sans A, Velazquez R. “Alternating Hemiplegia of Childhood: ATP1A3 Gene Analysis in 16 Patients.” Med Clin (Barc) April 23, 2014. (in Spanish) - [Alternating Hemiplegia of Childhood with a De Novo Mutation in APT1A3 and Changes in SLC2A1 Responsive to Ketogenic Diet](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-with-a-de-novo-mutation-in-apt1a3-and-changes-in-slc2a1-responsive-to-ketogenic-diet/) - Ulate-Campos A, Fons C, Artuch R, Castejon E, Martorell L, Ozelius L, Pascual J, Campistol J. “Alternating Hemiplegia of Childhood with a De Novo Mutation in APT1A3 and Changes in SLC2A1 Responsive to Ketogenic Diet.” Pediatric Neurology (December 6, 2013). - [Different phenotypes of neurological diseases, including alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism, caused by de novo ATP1A3 mutation in a family](https://ahckids.org/resources/different-phenotypes-of-neurological-diseases-including-alternating-hemiplegia-of-childhood-and-rapid-onset-dystonia-parkinsonism-caused-by-de-novo-atp1a3-mutation-in-a-family/) - Wei W, Zheng XF, Ruan DD, Gan YM, Zhang YP, Chen Y, Lin XF, Tang FQ, Luo JW, Li YF. 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Abstract: https://pubmed.ncbi.nlm.nih.gov/34783933/ - [Alternating Hemiplegia of Childhood Mutations Have a Differential Effect on Na(+).K(+)-ATPase Activity and Ouabain Binding](https://ahckids.org/resources/alternating-hemiplegia-of-childhood-mutations-have-a-differential-effect-on-na-k-atpase-activity-and-ouabain-binding/) - Weigand KM, Messchaert M, Swarts HG, Russel FG, Koenderink JB. “Alternating Hemiplegia of Childhood Mutations Have a Differential Effect on Na(+).K(+)-ATPase Activity and Ouabain Binding.” Biochim Biophys Acta (July 2014). - [ATP1A3 Mosaicism in Families with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/atp1a3-mosaicism-in-families-with-alternating-hemiplegia-of-childhood/) - Yang X, Yang X, Chen J, Li S, Zeng Q, Huang AY, Ye AY, Yu Z, Wang S, Jiang Y, Wu X, Wu Q, Wei L, Zhang Y. “ATP1A3 Mosaicism in Families with Alternating Hemiplegia of Childhood.” Clin Genet. 2019 Jul; 96(1): 43-52. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30891744 - [ATP1A3 Mutations and Genotype-Phenotype Correlation of Alternating Hemiplegia of Childhood in Chinese Patients](https://ahckids.org/resources/atp1a3-mutations-and-genotype-phenotype-correlation-of-alternating-hemiplegia-of-childhood-in-chinese-patients/) - Yang X, Gao H, Zhang J, Xu X, Liu X, Wu X, Wei L, Zhang Y. “ATP1A3 Mutations and Genotype-Phenotype Correlation of Alternating Hemiplegia of Childhood in Chinese Patients.” PLos ONE 9, no. 5 (May 2014). - [ATP1A3 Gene Mutations in Patients with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/atp1a3-gene-mutations-in-patients-with-alternating-hemiplegia-of-childhood/) - Yang X, Zhang Y, Yuan D, Xu X, Li S, Wei L, Wu Y, Xiong H, Liu X, Bao X, Jiang Y, Wu X. “ATP1A3 Gene Mutations in Patients with Alternating Hemiplegia of Childhood.” Zhongua Er Ke Za Zhi (November 2015). (Chinese) - [Fever-Induced Paroxysmal Weakness and Encephalopathy, a New Phenotype of ATP1A3 Mutation](https://ahckids.org/resources/fever-induced-paroxysmal-weakness-and-encephalopathy-a-new-phenotype-of-atp1a3-mutation/) - Yano S, Silver K, Young R, DeBrosse S, Ebel R, Swoboda K, Acsadi G. “Fever-Induced Paroxysmal Weakness and Encephalopathy, a New Phenotype of ATP1A3 Mutation.” Pediatric Neurology 73 (August 2017): 101-105. - [Psychiatric Disorders in Rapid-Onset Dystonia Parkinsonism](https://ahckids.org/resources/psychiatric-disorders-in-rapid-onset-dystonia-parkinsonism/) - Brashear A, Cook JF, Hill DF, Amonsah A, Snively BM, Light L, Boggs N, Suerken CK, Stacy M, Ozelius L, Sweadner KJ, McCall WV. “Psychiatric Disorders in Rapid-Onset Dystonia Parkinsonism.” Neurology (September 11, 2012): 1168-1173. - [Missense Variants in ATP1A3 and FXYD Gene Family are Associated with Childhood-onset Schizophrenia](https://ahckids.org/resources/missense-variants-in-atp1a3-and-fxyd-gene-family-are-associated-with-childhood-onset-schizophrenia/) - Chaumette B, Ferrafiat V, Ambalavanan A, Goldenberg A, Dionne-Laporte A, Spiegelman D, Dion PA, Gerardin P, Laurent C, Cohen D, Rapoport J, Rouleau GA. “Missense Variants in ATP1A3 and FXYD Gene Family are Associated with Childhood-onset Schizophrenia.” Molecular Psychiatry. 2018 Jun 12. Abstract: https://www.nature.com/articles/s41380-018-0103-8 - [Cognitive Deficits Caused by a Disease-Mutation in the a3 Na(+)/K(+)-ATPase Isoform](https://ahckids.org/resources/cognitive-deficits-caused-by-a-disease-mutation-in-the-a3-na-k-atpase-isoform-2/) - Holm TH, Isaksen TJ, Clerup S, Heuck A, Nissen P, Lykke-Hartmann K. “Cognitive Deficits Caused by a Disease-Mutation in the a3 Na(+)/K(+)-ATPase Isoform.” Scientific Reports (August 23, 2016). - [Knock-in Mouse Model of Alternating Hemiplegia of Childhood: Behavioral and Electrophysiologic Characterization](https://ahckids.org/resources/knock-in-mouse-model-of-alternating-hemiplegia-of-childhood-behavioral-and-electrophysiologic-characterization/) - Hunanyan Aresn, Fainberg N, Linabarger M, Arehart E, Leonard A, Adil S, Mikati M. “Knock-in Mouse Model of Alternating Hemiplegia of Childhood: Behavioral and Electrophysiologic Characterization.” Epilepsia. 2015 Jan; 56(1): 82-93. - [Cognitive, Adaptice, and Behavioral Profiles and Management of Alternating Hemiplegia of Childhood](https://ahckids.org/resources/cognitive-adaptice-and-behavioral-profiles-and-management-of-alternating-hemiplegia-of-childhood/) - Jasien J, Bonner M, D’alli R, Prange L, Mclean M, Sachdev M, Uchitel J, Ricano J, Smith B, Mikati M. “Cognitive, Adaptice, and Behavioral Profiles and Management of Alternating Hemiplegia of Childhood.” Developmental Medicine & Child Neurology. 2019 May; 61(5): 547-554. 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Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30862413 - [Long-term Effect of Flunarizine on Patients with Alternating Hemiplegia of Childhood in Japan](https://ahckids.org/resources/long-term-effect-of-flunarizine-on-patients-with-alternating-hemiplegia-of-childhood-in-japan/) - Sasaki M, Sakuragawa N, Osawa M. “Long-term Effect of Flunarizine on Patients with Alternating Hemiplegia of Childhood in Japan.” Brain & Development 23, no 5 (August 2001): 303-30. - [Childhood Rapid-Onset Ataxia: Expanding the Phenotypic Spectrum of ATP1A3 Mutations](https://ahckids.org/resources/childhood-rapid-onset-ataxia-expanding-the-phenotypic-spectrum-of-atp1a3-mutations/) - Schirinzi T, Graziola F, Nicita F, Travaglini L, Stregapede F, Valeriani M, Curatolo P, Bertini E, Vigevano F, Capuano A. “Childhood Rapid-Onset Ataxia: Expanding the Phenotypic Spectrum of ATP1A3 Mutations.” Cerebellum; 2018 Aug; 17(4): 489-493. Abstract: https://link.springer.com/article/10.1007%2Fs12311-018-0920-y - [Cell Biology and Dynamics of Neuronal Na+/K+-ATPase in Health and Diseases](https://ahckids.org/resources/cell-biology-and-dynamics-of-neuronal-na-k-atpase-in-health-and-diseases/) - Shrivastava A, Triller A, Melki R. “Cell Biology and Dynamics of Neuronal Na+/K+-ATPase in Health and Diseases.” Neuropharmacology. 2018 Dec 11. Abstract: https://www.sciencedirect.com/science/article/pii/S0028390818309079?via%3Dihub - [Direct Evidence of Impaired Neuronal Na/K-ATPase Pump Function in Alternating Hemiplegia of Childhood](https://ahckids.org/resources/direct-evidence-of-impaired-neuronal-na-k-atpase-pump-function-in-alternating-hemiplegia-of-childhood/) - Simmons CQ, Thompson CH, Cawthon BE, Westlake G, Swoboda KJ, Kiskinis E, Ess KC, George Al Jr. “Direct Evidence of Impaired Neuronal Na/K-ATPase Pump Function in Alternating Hemiplegia of Childhood.” Neurobiology of Disease. 2018 July; 115: 29-38. Abstract: https://www.sciencedirect.com/science/article/pii/S0969996118300779?via%3Dihub - [Fever-Induced Paroxysmal Weakness and Encephalopathy (FIPWE)-Part of a Phenotypic Continuum in Patients With ATP1A3 Mutations?](https://ahckids.org/resources/fever-induced-paroxysmal-weakness-and-encephalopathy-fipwe-part-of-a-phenotypic-continuum-in-patients-with-atp1a3-mutations/) - Sival DA, Vansenne F, Van der Hout AH, Tijssen MAJ, de Koning TJ. “Fever-Induced Paroxysmal Weakness and Encephalopathy (FIPWE)-Part of a Phenotypic Continuum in Patients With ATP1A3 Mutations?” Pediatric Neurology. 2018 Apr; 81: 57-58. Fulltext: https://www.pedneur.com/article/S0887-8994(17)31132-3/pdf - [α-synuclein Assemblies Sequester Neuronal α3-Na+/K+-ATPase and Impair Na+ Gradient](https://ahckids.org/resources/α-synuclein-assemblies-sequester-neuronal-α3-na-k-atpase-and-impair-na-gradient/) - Shrivastava A, Redeker V, Fritz N, Pieri L, Almeida LG, Spolidoro M, Liebmann T, Bousset L, Renner M, Léna C, Aperia A, Melki R, Triller A. “α-synuclein Assemblies Sequester Neuronal α3-Na+/K+-ATPase and Impair Na+ Gradient.” The EMBO Journal (August 31, 2015). - [“Impaired Cell Surface Expression of ATP1A3 Mutations Associated with Alternating Hemiplegia of Childhood](https://ahckids.org/resources/impaired-cell-surface-expression-of-atp1a3-mutations-associated-with-alternating-hemiplegia-of-childhood/) - Simmons C, Swoboda K, Ess K, George A. “Impaired Cell Surface Expression of ATP1A3 Mutations Associated with Alternating Hemiplegia of Childhood.” Biophysical Journal 108, no. 2 (January 2015). - [ATP1A3 Spectrum Disorders: A Video-Documented History of 7 Genetically Confirmed Early Onset Cases](https://ahckids.org/resources/atp1a3-spectrum-disorders-a-video-documented-history-of-7-genetically-confirmed-early-onset-cases/) - Stagnaro M, Pisciotta L, Gherzi M, Di Rocco M, Gurrieri F, Parrini E, Prato G, Veneselli E, De Grandis E. “ATP1A3 Spectrum Disorders: A Video-Documented History of 7 Genetically Confirmed Early Onset Cases.” Eur J Paediatr Neurol, 2018 Mar; 22(2): 264-271. Abstract: https://www.sciencedirect.com/science/article/pii/S1090379817316975?via%3Dihub - [Atp1a3-deficient Heterozygous Mice Show Lower Rank in the Hierarchy and Altered Social Behavior](https://ahckids.org/resources/atp1a3-deficient-heterozygous-mice-show-lower-rank-in-the-hierarchy-and-altered-social-behavior/) - Sugimoto H, Ikeda K, Kawakami K. “Atp1a3-deficient Heterozygous Mice Show Lower Rank in the Hierarchy and Altered Social Behavior.” Genes, Brain and Behavior. 2018 Jun; 17 (5): e12435. Abstract: https://onlinelibrary.wiley.com/doi/abs/10.1111/gbb.12435 - [Intermediate Phenotypes of ATP1A3 Mutations: Phenotype-Genotype Correlations](https://ahckids.org/resources/intermediate-phenotypes-of-atp1a3-mutations-phenotype-genotype-correlations/) - Termsarasab P, Yang AC, Frucht SJ. “Intermediate Phenotypes of ATP1A3 Mutations: Phenotype-Genotype Correlations.” Tremor and Other Hyperkinetic Movements (September 16, 2015). - [De Novo ATP1A3 and Compound Heterozygous NLRP3 Mutations in a Child with Autism Spectrum Disorder, Episodic Fatigue and Somnolence, and Muckle-Wells Syndrome](https://ahckids.org/resources/de-novo-atp1a3-and-compound-heterozygous-nlrp3-mutations-in-a-child-with-autism-spectrum-disorder-episodic-fatigue-and-somnolence-and-muckle-wells-syndrome/) - Torres A, Brownstein C, Tembulkar S, Graber K, et al. “De Novo ATP1A3 and Compound Heterozygous NLRP3 Mutations in a Child with Autism Spectrum Disorder, Episodic Fatigue and Somnolence, and Muckle-Wells Syndrome.” MGM Reports 2018 Sep; 15: 23-29. 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Fulltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573619/pdf/10.1177_2329048X211048068.pdf - [Functional Studies and Proteomics in Platelets and Fibroblasts Reveal a Lysosomal Defect with Increased Cathepsin-dependent Apoptosis in ATP1A3 Defective Alternating Hemiplegia of Childhood](https://ahckids.org/resources/functional-studies-and-proteomics-in-platelets-and-fibroblasts-reveal-a-lysosomal-defect-with-increased-cathepsin-dependent-apoptosis-in-atp1a3-defective-alternating-hemiplegia-of-childhood/) - Di Michele M, Goubau C, Waelkens E, Thys C, De Vos R, Overbergh L, Schyns T, Buyse G, Casaer P, Van Geet C, Freson K. “Functional Studies and Proteomics in Platelets and Fibroblasts Reveal a Lysosomal Defect with Increased Cathepsin-dependent Apoptosis in ATP1A3 Defective Alternating Hemiplegia of Childhood.” Journal of Proteomics (May 13, 2013). - [A Transgenic Mouse Model to Selectively Identify α3 Na,K-ATPase Expressing Cells in the Nervous System](https://ahckids.org/resources/a-transgenic-mouse-model-to-selectively-identify-α3-nak-atpase-expressing-cells-in-the-nervous-system/) - Dobretsov M, Hayar A, Kockara N, Kozhemyakin M, Light K, Patyal P, Pierce D, Wight P. “A Transgenic Mouse Model to Selectively Identify α3 Na,K-ATPase Expressing Cells in the Nervous System.” Neuroscience. 2018 Jul 19. 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No abstract available. - [A3Na+/K+-ATPase Deficiency Causes Brain Ventricle Dilation and Abrupt Embryonic Motility in Zebrafish](https://ahckids.org/resources/a3na-k-atpase-deficiency-causes-brain-ventricle-dilation-and-abrupt-embryonic-motility-in-zebrafish/) - Doganli C, et al. “A3Na+/K+-ATPase Deficiency Causes Brain Ventricle Dilation and Abrupt Embryonic Motility in Zebrafish.” J Biol Chem. 288, no. 13 (March 29, 2013): 8862-74. - [TP1A3-related disorders in the differential diagnosis of acute brainstem and cerebellar dysfunction](https://ahckids.org/resources/tp1a3-related-disorders-in-the-differential-diagnosis-of-acute-brainstem-and-cerebellar-dysfunction/) - Duat-Rodríguez A, Prochazkova M, Sebastian IP, Extremera VC, Legido MJ, Palero SR, Ortiz Cabrera NV. ATP1A3-related disorders in the differential diagnosis of acute brainstem and cerebellar dysfunction. Eur J Paediatr Neurol. 2021 Sep;34:105-109. Abstract: https://www.ejpn-journal.com/article/S1090-3798(21)00155-0/fulltext - [A Recurrent de novo Mutation in ATP1A3 Gene in a Mexican Patient with Alternating Hemiplegia of Childhood Detected by Massively Parallel Sequencing](https://ahckids.org/resources/a-recurrent-de-novo-mutation-in-atp1a3-gene-in-a-mexican-patient-with-alternating-hemiplegia-of-childhood-detected-by-massively-parallel-sequencing/) - Galaz-Montoya CI, Alcaraz-Estrada S, García-Montaño LA, Zenteno JC, Piña-Aguilar RE. “A Recurrent de novo Mutation in ATP1A3 Gene in a Mexican Patient with Alternating Hemiplegia of Childhood Detected by Massively Parallel Sequencing.” Bol Med Hosp Infant Mex. 2019; 76(1): 49-53. In Spanish. 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Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31238336 - [Next-generation AAV Vectors – Don’t Judge a Virus (only) by its Cover](https://ahckids.org/resources/next-generation-aav-vectors-dont-judge-a-virus-only-by-its-cover/) - Domenger C, Grimm D. “Next-generation AAV Vectors – Don’t Judge a Virus (only) by its Cover.” Hum Mol Genet. 2019 Jul 1. Ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31261383 - [AAV CRISPR Editing Resuces Cardiac and Muscle Function for 18 Months in Dystrophic Mice](https://ahckids.org/resources/aav-crispr-editing-resuces-cardiac-and-muscle-function-for-18-months-in-dystrophic-mice/) - Hakim CH, Wasala NB, Nelson CE, Wasala LP, Yue Y, Lounderman JA, Lessa TB, Dai A, Zhang K, Duan D. “AAV CRISPR Editing Resuces Cardiac and Muscle Function for 18 Months in Dystrophic Mice.” JCL Insight. 2018 Dec 6; 3(23). Fulltext: https://insight.jci.org/articles/view/124297 - [Adeno-Associated Virus (AAV) as a Vector for Gene Therapy](https://ahckids.org/resources/adeno-associated-virus-aav-as-a-vector-for-gene-therapy/) - Naso M, Tomkowicz B, Perry W, Shrohl W. “Adeno-Associated Virus (AAV) as a Vector for Gene Therapy.” BioDrugs. 2017; 31: 317-334. Fulltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548848/ - [AAV9 Vector: A Novel Modality in Gene Therapy for Spinal Muscular Atrophy](https://ahckids.org/resources/aav9-vector-a-novel-modality-in-gene-therapy-for-spinal-muscular-atrophy/) - Pattali R, Mou Y, Li XJ. “AAV9 Vector: A Novel Modality in Gene Therapy for Spinal Muscular Atrophy.” Gene Ther. 2019 Jun 26. Ahead of print. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31238336 - [A Wide Clinical Phenotype Spectrum in Patients with ATP1A2 Mutations](https://ahckids.org/resources/a-wide-clinical-phenotype-spectrum-in-patients-with-atp1a2-mutations/) - Al-Bulushi B, Al-Hashem A, Tabarki B. “A Wide Clinical Phenotype Spectrum in Patients with ATP1A2 Mutations.” Journal of Childhood Neurology (October 2013). - [A Novel Mutation in the ATP1A2 Gene Causes Alternating Hemiplegia of Childhood](https://ahckids.org/resources/a-novel-mutation-in-the-atp1a2-gene-causes-alternating-hemiplegia-of-childhood/) - Bassi MT, Bresolin N, Tonelli A. “A Novel Mutation in the ATP1A2 Gene Causes Alternating Hemiplegia of Childhood.” Journal of Medical Genetics 41 (2004,): 621-628. - [E-Z Access residential modifications/equipment including ramps, patient lifts, and stair lifts.](https://ahckids.org/resources/e-z-access-residential-modifications-equipment-including-ramps-patient-lifts-and-stair-lifts/) - E-Z Access residential modifications/equipment including ramps, patient lifts, and stair lifts. - [Headgear for injury prevention and special needs such as epilepsy.](https://ahckids.org/resources/headgear-for-injury-prevention-and-special-needs-such-as-epilepsy/) - Headgear for injury prevention and special needs such as epilepsy. - [Danmar head/neck support during AHC attacks of quad or dystonia](https://ahckids.org/resources/danmar-head-neck-support-during-ahc-attacks-of-quad-or-dystonia/) - Danmar head/neck support during AHC attacks of quad or dystonia - [Crash tested car seats, airplane seats and transit strollers for Safe Traveling](https://ahckids.org/resources/crash-tested-car-seats-airplane-seats-and-transit-strollers-for-safe-traveling/) - Crash tested car seats, airplane seats and transit strollers for Safe Traveling - [Custom wheelchair accessible conversions with your vehicle and new/used inventory](https://ahckids.org/resources/custom-wheelchair-accessible-conversions-with-your-vehicle-and-new-used-inventory/) - Custom wheelchair accessible conversions with your vehicle and new/used inventory - [Wheelchair accessible vehicles- new, used, and for sale by owner.](https://ahckids.org/resources/wheelchair-accessible-vehicles-new-used-and-for-sale-by-owner/) - Wheelchair accessible vehicles- new, used, and for sale by owner. - [Wheelchair accessible vehicles and mobility/transfer seating.](https://ahckids.org/resources/wheelchair-accessible-vehicles-and-mobility-transfer-seating/) - Wheelchair accessible vehicles and mobility/transfer seating. - [Wheelchair accessible vehicles- preowned or a specific conversion.](https://ahckids.org/resources/wheelchair-accessible-vehicles-preowned-or-a-specific-conversion/) - Wheelchair accessible vehicles- preowned or a specific conversion. - [Considerations in purchasing an accessible wheelchair vehicle/van.](https://ahckids.org/resources/considerations-in-purchasing-an-accessible-wheelchair-vehicle-van/) - Considerations in purchasing an accessible wheelchair vehicle/van. - [Tax strategies for parents of special needs kids](https://ahckids.org/resources/tax-strategies-for-parents-of-special-needs-kids/) - If you’re the parent of a child with special needs, there are some tax strategies to be aware of that can save your family money. For example, you can deduct the cost of many out-of-pocket expenses on your federal taxes. In this article, you’ll learn about deductions as well as other strategic considerations such as - [KetoVie for ketogenic diet formulas and foods](https://ahckids.org/resources/ketovie-for-ketogenic-diet-formulas-and-foods/) - KetoVie for ketogenic diet formulas and foods https://www.ketovie.com - [Functional Formularies ketogenic formulas](https://ahckids.org/resources/functional-formularies-ketogenic-formulas/) - Functional Formularies ketogenic formulas https://www.functionalformularies.com/product/keto-peptide - [Ketogenic diet medical formulas](https://ahckids.org/resources/ketogenic-diet-medical-formulas/) - Ketogenic diet medical formulas https://www.myketocal.com/ketogenic-diet-for-epilepsy - [National alliance of attorneys for special needs planning](https://ahckids.org/resources/national-alliance-of-attorneys-for-special-needs-planning/) - National alliance of attorneys for special needs planning https://www.specialneedsalliance.org - [ABLE national resource center](https://ahckids.org/resources/able-national-resource-center/) - ABLE national resource center http://ablenrc.org - [Special needs resource links of advocacy groups, government resources, and financial services](https://ahckids.org/resources/special-needs-resource-links-of-advocacy-groups-government-resources-and-financial-services/) - Special needs resource links of advocacy groups, government resources, and financial services https://www.specialneedsalliance.org/resources/helpful-links - [Educational tutorials, advocates, and future planning](https://ahckids.org/resources/educational-tutorials-advocates-and-future-planning/) - Educational tutorials, advocates, and future planning https://protectedtomorrows.com/ - [NORD’s MedicAlert assistance program](https://ahckids.org/resources/nords-medicalert-assistance-program/) - NORD’s MedicAlert assistance program https://rarediseases.org/wp-content/uploads/2021/02/NRD-2139-Medic-Alert-Assistance_FNL-1.pdf - [Wearable medical ID’s](https://ahckids.org/resources/wearable-medical-ids/) - Wearable medical ID’s https://store.medicalert.org/medical-id - [Seizure first aid training](https://ahckids.org/resources/seizure-first-aid-training/) - Seizure first aid training https://learn.epilepsy.com/ - [Gait trainers](https://ahckids.org/resources/gait-trainers/) - Gait trainers https://www.adaptivemall.com/seemore/gaittrainers1.html?product_list_limit - [Freedom Designs tilt-in-space wheelchairs.](https://ahckids.org/resources/freedom-designs-tilt-in-space-wheelchairs/) - Freedom Designs tilt-in-space wheelchairs. http://www.freedomdesigns.com/Wheelchairs.html - [Invacare power and manual wheelchairs](https://ahckids.org/resources/invacare-power-and-manual-wheelchairs/) - Invacare power and manual wheelchairs. https://pro.invacare.com/clp/Mobility - [Adaptive strollers and wheelchairs](https://ahckids.org/resources/adaptive-strollers-and-wheelchairs/) - Adaptive strollers and wheelchairs https://www.adaptivemall.com/allstrolpus.html - [Wheelchairs/adaptive strollers/gait trainers/seating.](https://ahckids.org/resources/wheelchairs-adaptive-strollers-gait-trainers-seating/) - Wheelchairs/adaptive strollers/gait trainers/seating. https://www.etac.com/en-us/us/products/pediatrics/seating/ - [Bath and shower chairs](https://ahckids.org/resources/bath-and-shower-chairs/) - Bath and shower chairs. - [Etac shower and bath chairs and bathing equipment.](https://ahckids.org/resources/etac-shower-and-bath-chairs-and-bathing-equipment/) - Etac shower and bath chairs and bathing equipment. - [Bruno indoor and outdoor stair lifts.](https://ahckids.org/resources/bruno-indoor-and-outdoor-stair-lifts/) - Bruno indoor and outdoor stair lifts. - [Invacare wheelchairs, lifts, home care beds.](https://ahckids.org/resources/invacare-wheelchairs-lifts-home-care-beds/) - Invacare wheelchairs, lifts, home care beds. - [Surehands home mobility lifts with options for ceiling, mobile, or wall to wall with a wide range of slings and body support.](https://ahckids.org/resources/surehands-home-mobility-lifts-with-options-for-ceiling-mobile-or-wall-to-wall-with-a-wide-range-of-slings-and-body-support/) - Surehands home mobility lifts with options for ceiling, mobile, or wall to wall with a wide range of slings and body support. - [ARC](https://ahckids.org/resources/arc/) - Public policy, advocacy, and resource group. ARC http://www.thearc.org - [The Oley Foundation](https://ahckids.org/resources/the-oley-foundation/) - The Oley Foundation Home nutrition support and advocacy group https://oley.org - [Donate wheelchairs/special needs equipment.](https://ahckids.org/resources/donate-wheelchairs-special-needs-equipment/) - Donate wheelchairs/special needs equipment. https://www.joniandfriends.org/support-us/donate-a-wheelchair/ - [The Oley Foundation](https://ahckids.org/resources/the-oley-foundation-2/) - Equipment exchange or donation of home IV or feeding tube supplies. The Oley Foundation https://oley.org/page/Equipment_Exchange - [Early Intervention resources.](https://ahckids.org/resources/early-intervention-resources/) - Early Intervention resources. https://www.parentcenterhub.org/ei-overview - [Special education advocacy and training](https://ahckids.org/resources/special-education-advocacy-and-training/) - Special education advocacy and training https://www.wrightslaw.com/advoc.htm - [Resource library](https://ahckids.org/resources/resource-library/) - Resource library https://www.parentcenterhub.org/resourcelibrary/index/i/i2/ - [Home School Legal Defense Association for legal protection and educational support](https://ahckids.org/resources/home-school-legal-defense-association-for-legal-protection-and-educational-support/) - Home School Legal Defense Association for legal protection and educational support https://hslda.org - [Home school special needs resources](https://ahckids.org/resources/home-school-special-needs-resources/) - Home school special needs resources https://hslda.org/content/strugglinglearner/default.asp - [Tranquility incontinence supplies and Medicaid coverage](https://ahckids.org/resources/tranquility-incontinence-supplies-and-medicaid-coverage/) - Tranquility incontinence supplies and Medicaid coverage. https://tranquilityproducts.com/medicaid-incontinence-supplies-guide - [Northshore incontinence bed pads](https://ahckids.org/resources/northshore-incontinence-bed-pads/) - Northshore incontinence bed pads https://www.northshorecare.com/incontinence-products/incontinence-bed-pads - [Oley Foundation for home nutrition support- intravenous and enteral tube feeding](https://ahckids.org/resources/oley-foundation-for-home-nutrition-support-intravenous-and-enteral-tube-feeding/) - Oley Foundation for home nutrition support- intravenous and enteral tube feeding. https://oley.org/default.aspx - [Functional Formularies organic whole foods plant-based formulas](https://ahckids.org/resources/functional-formularies-organic-whole-foods-plant-based-formulas/) - Functional Formularies organic whole foods plant-based formulas https://www.realfoodblends.com - [Real food blends](https://ahckids.org/resources/real-food-blends/) - Real food blends https://www.realfoodblends.com - [The Charlie Foundation for ketogenic therapies](https://ahckids.org/resources/the-charlie-foundation-for-ketogenic-therapies/) - The Charlie Foundation for ketogenic therapies https://charliefoundation.org - [Support families and healthcare professionals to advance the ketogenic diet for treatment of pediatric epilepsy.](https://ahckids.org/resources/support-families-and-healthcare-professionals-to-advance-the-ketogenic-diet-for-treatment-of-pediatric-epilepsy/) - Support families and healthcare professionals to advance the ketogenic diet for the treatment of pediatric epilepsy. http://ketohope.org - [Advanced Ketogenic Therapies](https://ahckids.org/resources/advanced-ketogenic-therapies/) - Advanced Ketogenic Therapies for consultation and monitoring of ketogenic diet https://advancedketogenictherapies.com/ ## Events - [𝗪𝗵𝘆 𝗶𝘀 𝗺𝘆 𝗰𝗵𝗶𝗹𝗱 𝗯𝗲𝗵𝗮𝘃𝗶𝗻𝗴 𝘁𝗵𝗶𝘀 𝘄𝗮𝘆?](https://ahckids.org/event/𝗪𝗵𝘆-𝗶𝘀-𝗺𝘆-𝗰𝗵𝗶𝗹𝗱-𝗯𝗲𝗵𝗮/) - 📅 𝗔𝘂𝗴𝘂𝘀𝘁 𝟭𝟯𝘁𝗵 🕖 𝟳:𝟬𝟬 𝗽𝗺 𝗘𝗗𝗧 Register Here - https://tinyurl.com/m7dzhcd4 𝗪𝗵𝘆 𝗶𝘀 𝗺𝘆 𝗰𝗵𝗶𝗹𝗱 𝗯𝗲𝗵𝗮𝘃𝗶𝗻𝗴 𝘁𝗵𝗶𝘀 𝘄𝗮𝘆? It's a question many AHC parents have asked themselves. Behavior can be one of the most confusing and emotionally exhausting parts of living with AHC. It can change over time, look different from one child to the - [AHCF Family Meeting 2027 - Bigger in Texas. Stronger Together.](https://ahckids.org/event/ahcf-family-meeting-2027-bigger-in-texas-stronger-together/) - One year from now, we'll be calling this place home. 💜 We're excited to share the host hotel for the 2027 AHC Foundation Family Meeting! 🏨 Marriott CityPlace at Springwoods Village 📍 Houston, Texas 📅 June 23–26, 2027 Welcome to the AHC Foundation Family Meeting where the AHC community comes together—to learn from leading experts, - [AHCF Webinar: What does your child's genetic test actually mean?](https://ahckids.org/event/what-does-your-childs-genetic-test-actually-mean/) - Your Child's AHC Genetic Results: What They Mean—and Why They Matter 📅 Tuesday, July 28 🕖 7:00 PM EDT https://accountingdepartment.zoom.us/meeting/register/-sVoMJcKSkGgMuvXrLIuAg Many individuals with Alternating Hemiplegia of Childhood (AHC) have a change, or mutation, in the ATP1A3 gene—but understanding what those results mean can feel overwhelming. Join us for a special webinar with Suzanne D. DeBrosse, MD, - [AHCF Webinar - Dr Mohamad Mikati](https://ahckids.org/event/ahcf-webinar-with-dr-mohamed-mikati-understanding-the-natural-history-study-for-patients-families-and-clinical-trials/) - “What We've Learned from the outcome study of 115 Individuals with AHC: Insights for Families and Future Treatments" View Here - https://www.youtube.com/watch?v=k12e9nL-L48&t=228s The Natural History Study of AHC which was published recently (https://onlinelibrary.wiley.com/doi/epdf/10.1002/cns3.70037) and was highlighted as the top article of the year in the North American Child Neurology Society, has major implications for the - [Protected Tomorrows Parent University - Education: Back to SchoolTips](https://ahckids.org/event/protected-tomorrows-parent-university-education-back-to-schooltips/) - Description - “School” can mean many things: - If your child is young, what is an IEP? - If your child is older, what can you expect to be available? - Are there really appropriate school experiences for your child after high school? Date & Time Aug 13, 2026 12:00 PM Central Time (US and - [Caregivers Compass Begins Soon - Register Now](https://ahckids.org/event/caregivers-compass-begins-soon-register-now/) - Registration is now open for our Caregiver’s Compass, a free virtual course for parents and caregivers of children with complex health care needs. Caregiving often means focusing on everyone else’s needs first. This course gives caregivers time to step back and learn ways to support their own well-being while continuing to care for someone they - [14th ATP1A3 Symposium](https://ahckids.org/event/14th-atp1a3-symposium/) - The 14th International ATP1A3 Symposium, which brings together researchers, clinicians, families and associations from around the world around rare diseases linked to the ATP1A3 gene , is fast approaching. The French AHC Family Association (AFHA) is honoured and delighted to announce that the 14th ATP1A3 in disease Symposium will take place at the at the Pitié-Salpêtrière Hospital in - [Family Circle is Going on Summer Break!](https://ahckids.org/event/family-circle-is-going-on-summer-break/) - AHC families and caregivers, Family Circle will be on summer break from June through August, and we look forward to gathering again in September! We. Are. Here. If you're looking for connection, support, or resources during the summer months, please reach out to AHCF's Family Support Team at heather@ahckids.org. Wishing you a safe, relaxing, and - [Protected Tomorrows Parent University - ABLE Account Webinar](https://ahckids.org/event/protected-tomorrows-parent-university-able-account-webinar/) - Protected Tomorrows Parent University is presenting a free webinar on June 11th. Everyone who has an interest in the Special Needs Community is invited. In this important session about ABLE Accounts, we will cover: The basics of ABLE How ABLE differs by state How to stay out of trouble. What is the best way to - [AHCF Family Circle – You’re Invited – 5/13/26](https://ahckids.org/event/ahcf-family-circle-youre-invited-5-13-26-2/) - Join us for our next AHCF Family Circle on Wednesday, May 13th at 10am PST/ 12pm CST/ 1pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates at Heather@ahckids.org. - [2026 Parent University - Vacations and Respite Ideas for the Whole Family](https://ahckids.org/event/2026-parent-university-vacations-and-respite-ideas-for-the-whole-family/) - In this exciting session about respite, we will cover: Have you ever thought it is just not possible to have a vacation? Or maybe just some respite? How does that fit into your life? Where can you find resources that match the needs of your family? Click Here To Register - [What’s so Special about Special Needs Planning!](https://ahckids.org/event/whats-so-special-about-special-needs-planning/) - Mary Anne Ehlert of Protected Tomorrows presents: What’s So Special about Special Needs Planning. Webinar event: May 20th at 6:00 p.m. Central Time Registration link: https://us02web.zoom.us/webinar/register/WN_r_SXL-kTQ6W02_onrknsEQ Join us for an enlightening presentation that includes: An overview of the Protected Tomorrows Mission and an understanding of how we work with families to Construct a Framework for - [AHCF Family Circle - You're Invited - 5/13/26](https://ahckids.org/event/ahcf-family-circle-youre-invited-5-13-26/) - Join us for our next AHCF Family Circle on Wednesday, May 13th at 10am PST/ 12pm CST/ 1pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates at Heather@ahckids.org. - [AHCF Family Circle - You're Invited - 3/11/26](https://ahckids.org/event/ahcf-family-circle-youre-invited-21126-copy/) - Join us for our next AHCF Family Circle on Wednesday, March 11th at 10am PST/ 12pm CST/ 1pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates at Heather@ahckids.org. - [Parent University – Let’s Get Clear Together On Government Benefits](https://ahckids.org/event/parent-university-lets-get-clear-together-on-government-benefits/) - In this in-depth session about government benefits, we will cover: Can you ever know everything about the benefits available to you and your family? How do you know if you have applied for everything possible? We’ll be talking about SSI, SSDI, DAC, Medicare, Medicaid, SNAP, and more. When: April 16, 2026 12:00 pm - 1:00 - [Live Q & A Webinar with Denise Potter, RDN - Ketogenic Therapy](https://ahckids.org/event/9368/) - Bring your questions and join the conversation. Date: April 8th Time: 1:00 pm EDT Register: https://tinyurl.com/bdex5x99 Join us for a special 𝗹𝗶𝘃𝗲 𝗤&𝗔 𝘄𝗲𝗯𝗶𝗻𝗮𝗿 𝘄𝗶𝘁𝗵 𝗗𝗲𝗻𝗶𝘀𝗲 𝗣𝗼𝘁𝘁𝗲𝗿, 𝗥𝗗𝗡, founder of 𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗞𝗲𝘁𝗼𝗴𝗲𝗻𝗶𝗰 𝗧𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀, who brings over 𝟯𝟯 𝘆𝗲𝗮𝗿𝘀 𝗼𝗳 𝗲𝘅𝗽𝗲𝗿𝗶𝗲𝗻𝗰𝗲 𝗮𝘀 𝗮 𝗥𝗲𝗴𝗶𝘀𝘁𝗲𝗿𝗲𝗱 𝗗𝗶𝗲𝘁𝗶𝘁𝗶𝗮𝗻 𝗡𝘂𝘁𝗿𝗶𝘁𝗶𝗼𝗻𝗶𝘀𝘁 𝗮𝗻𝗱 𝟭𝟳 𝘆𝗲𝗮𝗿𝘀 𝘀𝗽𝗲𝗰𝗶𝗮𝗹𝗶𝘇𝗶𝗻𝗴 𝗶𝗻 𝗸𝗲𝘁𝗼𝗴𝗲𝗻𝗶𝗰 𝗺𝗲𝘁𝗮𝗯𝗼𝗹𝗶𝗰 𝘁𝗵𝗲𝗿𝗮𝗽𝘆. When epilepsy - [How Your AHC Data Drives Research and Improves Care - Webinar 3/25](https://ahckids.org/event/how-your-ahc-data-drives-research-and-improves-care-webinar-3-25/) - Join us for an upcoming 𝗔𝗛𝗖 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗪𝗲𝗯𝗶𝗻𝗮𝗿 featuring 𝗗𝗿. 𝗡𝘂𝘁𝗮𝗻 𝗦𝗵𝗮𝗿𝗺𝗮 𝗳𝗿𝗼𝗺 𝗛𝗮𝗿𝘃𝗮𝗿𝗱 𝗨𝗻𝗶𝘃𝗲𝗿𝘀𝗶𝘁𝘆 𝗮𝗻𝗱 𝗠𝗮𝘀𝘀𝗮𝗰𝗵𝘂𝘀𝗲𝘁𝘁𝘀 𝗚𝗲𝗻𝗲𝗿𝗮𝗹 𝗛𝗼𝘀𝗽𝗶𝘁𝗮𝗹. 📅 March 25th ⏰ 7:00 PM EDT Register Here: 🔗 https://tinyurl.com/ypdh3wua Dr. Sharma will introduce a 𝗻𝗲𝘄 𝘁𝘄𝗼-𝘆𝗲𝗮𝗿 𝗔𝗛𝗖 𝘀𝘁𝘂𝗱𝘆 designed to better understand how AHC evolves from childhood through adulthood. This first-of-its-kind study will bring - [Parent University - Good Debt vs Bad Debt in Special Needs Trust](https://ahckids.org/event/parent-university-good-debt-vs-bad-debt-in-special-needs-trust/) - Demystifying debt 💵 Join Protected Tomorrows’ Parent University Class 3 for a candid conversation regarding debt. In this class, we will discuss: ➡️Is there really such a thing as good debt? ➡️ When should you pay down debt? ➡️ Is there a creative way to use debt to fund a special needs trust? 📅 March - [RARE Advocate Development (RAD) Brain Workshop](https://ahckids.org/event/rare-advocate-development-rad-brain-workshop/) - We’re excited to share that the AHC Foundation has been invited to attend the RAREAdvocate Development (RAD) Brain Workshop this May in Boston! This three-day intensive, hosted by Global Genes, the Rare Epilepsy Network (REN), and Mahzi Therapeutics, brings together rare disease advocates who are actively accelerating research in their neurological conditions. From drug development - [The Caregiver’s Compass Training](https://ahckids.org/event/the-caregivers-compass-training/) - The Caregiver’s Compass is a free, four-week virtual course designed for parents and caregivers who want practical tools and meaningful connection. Throughout this interactive series, caregivers will: • Learn strategies for managing stress • Strengthen communication skills • Build tools to support mental wellbeing • Connect in a supportive, community-centered space Each live session is - [🫀 Heart 2 Heart Webinar: Cardiac Care & AHC](https://ahckids.org/event/🫀-heart-2-heart-webinar-cardiac-care-ahc/) - 🫀Join AHCF for a heart-to-heart conversation with Dr. Andrew Landstrom, focused on the unique cardiac concerns faced by individuals living with Alternating Hemiplegia of Childhood. Wednesday, February 25 @ 6:00 PM EST Please click the link below to register for the event: https://tinyurl.com/5863hv3z Registration is required. All registrants will receive a confirmation email with the Zoom - [Parent University - Estate Planning](https://ahckids.org/event/parent-university-estate-planning/) - All about estate planning 📄 Join Protected Tomorrows’ Parent University Class 2 for an informational session breaking down the different components of estate planning. In this class, we will discuss: ➡️ What are the components ➡️ How to find the right attorney ➡️ What needs to be updated and when 📅 February 12, 2026 ⏰ - [AHCF Apparel Pop-Up Store is Open!](https://ahckids.org/event/ahcf-apparel-pop-up-store-is-open/) - You asked—and we’re excited to say it’s back 💙 Our apparel store is officially OPEN as a limited-time pop-up, launched to honor the meaningful days between International AHC Day and Rare Disease Day. This collection is more than apparel. It’s about visibility, connection, and proudly supporting the AHC community. Many of these designs are fan favorites, brought back - [AHC Valentine’s Day Card Exchange](https://ahckids.org/event/ahc-valentines-day-card-exchange/) - Hello AHC families! It’s time for the AHC Valentine’s Day card exchange. This tradition began as a way to keep our children connected between family meetings, back before social media. Everyone is welcome to join, regardless of age! Each participant sends a card to all others—some choose photo cards, handmade creations, stickers, or drawings and - [AHCF Family Circle - You're Invited - 1/14/26](https://ahckids.org/event/ahcf-family-circle-youre-invited-1-14-26/) - Join us for our next AHCF Family Circle on Wednesday, January 14th at 10am PST/ 12pm CST/ 1pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates at Heather@ahckids.org. - [Season of Giving - Help Ignite the Start of AHC Research Projects in 2026](https://ahckids.org/event/season-of-giving-help-ignite-the-start-of-ahc-research-projects-in-2026/) - Our year-end campaign is here — a season of hope, movement, and possibility for every individual living with Alternating Hemiplegia of Childhood. You Can Help Light the Path in Three ways: Send a letter to family members, friends, colleagues, or school/church members - asking for help in lighting the path - then ask them to - [Light the Path for AHC Research in 2026!](https://ahckids.org/event/light-the-path-for-ahc-research-in-2026/) - Dear Friend of the AHC Foundation, As 2025 draws to a close, we reflect on the incredible progress made during our 30th anniversary year—and the many families who continue to face the daily challenges of Alternating Hemiplegia of Childhood (AHC). Every step forward in research brings renewed hope for better treatments, improved quality of life, - [AHCF Family Circle - You're Invited!](https://ahckids.org/event/ahcf-family-circle-youre-invited/) - Join us for our next AHCF Family Circle on Wednesday, December 10th at 10am PST/ 12pm CST/ 1pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates at Heather@ahckids.org. - [Hands of Hope for AHC - Add Your Photo](https://ahckids.org/event/hands-of-hope-for-ahc-add-your-photo/) - It starts with our hands — and our hearts. For the first time, The AHC Foundation, Cure AHC, and AHC Europe are joining together in one global movement — Hands of Hope — to show the world what hope looks like when we hold it together. Now, it’s your turn: What hands uplift you and - [“AHC and Epilepsy, Clarity and Confusion”](https://ahckids.org/event/ahc-and-epilepsy-clarity-and-confusion/) - 💜 Join us for a live webinar Wednesday the 19th @ 1:pm EST. Dr. Kevin Ess, a leading neurologist in Epilepsy and Alternating Hemiplegia of Childhood (AHC) will share insights from the front lines of research and care — what’s next for families and the path to better treatments, then answer your questions! Dr. Kevin - [AHCF Family Circle](https://ahckids.org/event/8701/) - You're Invited! Join us for our next AHCF Family Circle on Wednesday, November 12th at 10am PST/ 12pm CST/ 1pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates - ["Can I Have Joy/Peace Without Being Naive or In Denial?"](https://ahckids.org/event/can-i-have-joy-peace-without-being-naive-or-in-denial/) - Parenting a child with AHC means facing moments of stress, resilience, purpose, and anticipatory grief. Join counselor Brad Thompson, MA, LPC-S for a heartfelt session on finding joy and peace — even through naivety and denial. Practical tools. Real talk. Hope you can hold on to. Wednesday, October 22 12:00 – 1:00 PM CST (40-minute - [Parent University - Sibling Panel - The Future without us](https://ahckids.org/event/parent-university-sibling-panel-the-future-without-us/) - Parent University: Sibling Panel – The Future Without UsMany of us hope that siblings will one day step into our shoes — but how do they really feel about that? What do they need to know, and when is the right time to share it?Join Protected Tomorrows’ Parent University on October 9th, 12:00–1:00 PM CT - [AHCF Family Circle](https://ahckids.org/event/ahcf-family-circle/) - You're Invited! Join us for our next AHCF Family Circle on Wednesday, October 8th at 10am PST/ 12pm CST/ 1pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates - [Dystonia Webinar September 24](https://ahckids.org/event/dystonia-webinar-september-24/) - Registration is Now Open for the Dr. Nutan Sharma Webinar! We are thrilled to announce that registration is now open for our upcoming webinar with Dr. Nutan Sharma, a world-renowned leader in movement disorders. ✨ The webinar is free to attend, but registration is required. When you register, you will immediately receive a confirmation email - [NORD Breakthrough Summit](https://ahckids.org/event/nord-breakthrough-summit/) - Check out this information-filled event! - [ATP1A3 Symposium - September 15 & 16](https://ahckids.org/event/atp1a3-symposium-september-15-16/) - The 13th ATP1A3 in Disease Symposium will take place (virtually) on 15 and 16 September 2025 in Cairns, Australia, in conjunction with the 17th International Meeting on P-Type ATPases in Health & Disease The Program of the 13th Symposium is set up to allow speakers and participants from Australia and Asia Pacific , but also from all other parts of - [Time is Running Out! Family Meeting 2025](https://ahckids.org/event/family-meeting-2025/) - Last chance! Don't miss the opportunity to meet with the expert AHC community of providers and parents on June 19, 2025. We have researchers, treating physicians, family support and more all speaking on the latest information, and helpful tips and tricks, regarding AHC. Please don’t miss this opportunity to spend time with other AHC parents, - [Family Fun in Cincinnati: A Perfect Getaway! ](https://ahckids.org/event/8221/) - Looking for the perfect family vacation? Cincinnati is a hidden gem packed with unforgettable experiences for kids and parents alike! Explore & Learn – From hands-on exhibits at the Cincinnati Museum Center to the wonders of the Newport Aquarium, every day is an adventure! Outdoor Fun – Take in the stunning riverfront at Smale Park, ride - [AHCF Family Meeting 2023](https://ahckids.org/event/ahcf-family-meeting-2023/) - June 22-25 Embassy Suites Glendale Los Angeles, California Learn More About Family Meetings - [Support Group for AHC, Monthly Family Circle](https://ahckids.org/event/support-group-for-ahc-monthly-family-circle/) - Join us for our next AHCF Family Circle on Saturday, September 28th at 11am PST/ 1pm CST/ 2pm EST. This is a support group for parents of individuals with AHC. Share your challenges and joys in this informal setting. Connect with others on this journey! If you have questions, please email Heather Gates at Heather@ahckids.org. - [Join the Freedom Run on July 6](https://ahckids.org/event/join-the-freedom-run-on-july-6/) - A 4th of July run for a cure benefiting Alternating Hemiplegia of Childhood Foundation. - [Empowered Parenting: Thriving as a Single Parent Raising a Rare Disease Child](https://ahckids.org/event/empowered-parenting-thriving-as-a-single-parent-raising-a-rare-disease-child/) - The National Organization for Rare Disorders (NORD) invites you to join us for a comprehensive, supportive, and closed-door discussion about raising a rare disease child or children as a single parent. Date: Thursday, June 27, 2024 Time: 7:00 p.m. - 8:05 p.m. ET Location: Virtual via Zoom You will hear from single rare parents about - [Warriors for Kathryn](https://ahckids.org/event/warriors-for-kathryn-2/) - FRIDAY FEBRUARY 2,2024 5PM Expo Hall - 2691 N. Park Rd. Connersville, IN Help support a worthy cause through Warriors for Kathryn at Expo Hall in Connersville! Follow the event page on Facebook at https://fb.me/e/3F5hfAh9p for more information on Wine Bingo, Texas Hold’em, Dinner, Basket Raffle, Quilt Raffle, and more! - [Warriors for Kathryn Quilt Raffle](https://ahckids.org/event/warriors-for-kathryn-quilt-raffle/) - Kaleidoscope of Hope is the name of this year's quilt to be raffled off at the Warriors for Kathryn event on February 2, 2024, in Cornersville, Indiana. Warriors for Kathryn 2024 Quilt Raffle Information: Quilting tradition asks for a name to be selected for a quilt. “Kaleidoscope of Hope” is the name given to this - [Valentine's Exchange 2024](https://ahckids.org/event/valentines-exchange-2024/) - Hello AHC families! It's time for the AHC Valentine's Day card exchange. This started as a way to keep our children connected between family meetings (before social media). All ages can participate! Each child/adult sends a card to all participating. Some send a photo card, handmade card, stickers, or drawing/coloring. To participate, email your child's - [Rare Disease Day](https://ahckids.org/event/rare-disease-day/) - Join people around the world raising awareness for AHC and thousands of rare diseases. Share our Facebook and Instagram posts! - [Webinar - Grief and Raising Special Needs Children](https://ahckids.org/event/webinar-grief-and-raising-special-needs-children/) - Brad Thompson will lead what he calls a “guided dialogue” to explore the chronic nature of grief as it relates to families raising children with special healthcare needs. This will include the journey to acceptance of our situation and the challenges to that acceptance. It will also include the importance of finding real meaning in - [Race to End AHC](https://ahckids.org/event/race-to-end-ahc/) - September 30, 2023 Annual virtual race to raise funds and awareness to end AHC. - [Warriors for Kathryn](https://ahckids.org/event/warriors-for-kathryn/) - FRIDAY FEBRUARY 3, 2023 5PM Expo Hall - 2691 N. Park Rd. Connersville, IN Help support a worthy cause through Warriors for Kathryn at Expo Hall in Connersville! Follow the event page on Facebook at https://fb.me/e/3F5hfAh9p for more information on Wine Bingo, Texas Hold’em, Dinner, Basket Raffle, Quilt Raffle, and more! - [International AHC DAY](https://ahckids.org/event/international-ahc-day/) - January 18, 2023 Join us as we spread awareness and raise funds to end AHC on the anniversary of the discovery of the gene that causes AHC: ATP1A3. - [Happy Birthday Sean!](https://ahckids.org/event/happy-birthday-sean/) - June 1, 2023 Sean Gerber turns 20 today, join us in wishing her a happy birthday and give the gift of hope for an AHC future by donating to AHCF. - [Happy Birthday Daxton!](https://ahckids.org/event/happy-birthday-daxton/) - December 24, 2023 Daxton Douglas turns 3 today, join us in wishing her a happy birthday and give the gift of hope for an AHC future by donating to AHCF. - [Happy Birthday Joey!](https://ahckids.org/event/happy-birthday-joey/) - December 25, 2023 Joey Hawk turns 11 today, join us in wishing him a happy birthday and give the gift of hope for an AHC free future by donating to AHCF. - [Happy Birthday Kiley!](https://ahckids.org/event/happy-birthday-kiley/) - May 10, 2023 Kiley Andrasco turns 22 today, join us in wishing her a happy birthday and give the gift of hope for an AHC free future by donating to AHCF. - [Valentine's Card Exchange](https://ahckids.org/event/valentines-card-exchange/) - February 1-14 AHCF parent, Heather Gates, and daughter Jocelyn, host an annual Valentine's Card exchange for people with AHC of all ages! 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