The AHCF Medical Advisory Board is comprised of recognized authorities of the Alternating Hemiplegia of Childhood (AHC) disorder. At leading academic facilities, clinical hospitals, and research institutions; all have devoted their time and medical expertise to improving the lives of people afflicted with AHC.
The role of the AHCF Medical Advisory Board is to provide strategic advice and counsel, as requested by the AHCF Board of Directors, to support the mission of the Alternating Hemiplegia of Childhood Foundation.
Matthew T. Sweney, MD., M.S.
University of Utah, Division of Pediatric Neurology
Clinical Instructor/Clinical Neurophysiology Fellow
Primary Children’s Medical Canter
100 N Mario Capecchi Drive
Salt Lake City, Utah 84113
Matthew Thomas Sweney, MD, MS is originally from Lincoln, NE, and attended the University of Nebraska-Lincoln where he received his BS in Biosystems Engineering. Afterward, Matthew attended the University of Minnesota-Twin Cities and received his Masters in Biomedical Engineering. He returned to Nebraska and attended the University of Nebraska, College of Medicine, where he received his MD in 2004. After graduation, Matthew completed his pediatric residency at the combined University of Nebraska-Creighton University training program. He came to the University of Utah in 2007 and completed a one year Research Fellowship studying Alternating Hemiplegia of Childhood with Katherine Swoboda, MD prior to completing his fellowship in general child neurology in 2011. Following his child neurology, he completed a one-year clinical neurophysiology fellowship with focus on electroencephalography and epilepsy. He is currently appointed as an assistant professor of pediatric neurology with special emphasis on epilepsy.
Dr Sweney’s past research interests have included ocular drug delivery and neuroprotective measures in stroke management during his graduate training. He has published on congenital malformations and steroid use in neonatal critical care during his general pediatric training. Currently, he continues to investigate the genetic and clinical aspects of Alternating Hemiplegia of Childhood as well as focusing efforts on improving epilepsy care for children in Utah and surrounding areas. He is board certified in both general pediatrics and neurology with special emphasis on child and adolescent care.
A list of selected publications can be found here https://www.doximity.com/pub/
Kenneth Silver, MD, MSc, F.R.C.P.
Program Director,Child Neurology Training Program,Associate Professor
Departments of Pediatrics and Neurology, University of Chicago
Comer Children’s Hospital, Chicago Ill.
Office Postal Address:
University of Chicago Medical Center
5841 South Maryland Avenue Chicago, Ill. 60637-MC3055
Phone: 773-702-6487, Fax 773-702-4786
A Pediatric Neurologist, Kenneth Silver, MD, specializes in neuromuscular disorders, cerebral palsy, neurogenic disorders, movement disorders, headaches and epilepsy. Dr Silver is also an active researcher and is fluent in English and French. He has been in practice since 1979. He completed his MD at the University of Saskatchewan, Canada, followed by residency and fellowship at Children’s Health Center in Winnipeg, Canada, Montreal Children’s Hospital and the Montreal Neurological Institute. He is a member of the American Academy of Neurology and the American Headache Society.
A list of selected publications can be found here http://www.
Frederick Andermann, O.C., M.D., F.R.C.P.(C)
Professor of Neurology and Paediatrics,
Director, Epilepsy Service
Montreal Neurological Hospital & Institute
Dr. Andermann is a Professor in the Departments of Neurology and Neurosurgery, and Pediatrics at McGill University. He is also the Director of the Epilepsy Service and the Epilepsy Unit at the Montreal Neurological Institute and Hospital. Dr. Andermann is one of the world’s foremost leaders in the description, diagnosis and treatment of epilepsy. He has shown a remarkable ability to identify syndromes and assemble multidisciplinary teams of researchers to conduct further clinical investigations. The results of his inquiries in such areas as cortical dysplasias, progressive myoclonic epilepsies, epilepsy surgery and genetically determined disorders have been published in six books and over 500 articles. His monographs on alternating hemiplegia, Rasmussen’s Syndrome and migraine-epilepsy syndromes have contributed significantly to understanding these disorders and have led to further research in these areas. Much of Dr. Andermann’s pioneering investigations into epilepsy have been in collaboration with his wife and colleague, Dr. Eva Andermann. They are best known for identifying in the 1970s what later came to be known as Andermann’s syndrome, a debilitating and degenerative disease of the nervous system concentrated in patients of the Saguenay and Charlevoix regions of Quebec.
Dr. Andermann has been a key figure in training neurologists and in the development of epilepsy programs around the world. Through his vision and leadership, he has expanded his sphere of expertise by gathering around him a strong group of colleagues at the MNI that provide a rich multidisciplinary environment. Dr. Andermann’s reputation and the environment he has built at the Neuro with Dr. Eva Andermann, have attracted fellows from around the world. He has trained fellows from more than 15 countries, many of whom have gone on to distinguished academic careers at Harvard University, University of Melbourne, University College Hospitals in London and Tokyo Women’s Medical College.
Dr. Andermann has been recognized for his outstanding achievements with the 2003 Prix Wilder Penfield, the 2000 William G. Lennox Award from the American Epilepsy Society, the 1999 Penfield Award for Contribution in Outstanding Canadian Epileptology from the Canadian League Against Epilepsy, and the 1995 Distinguished Clinical Investigator Award from the American Epilepsy Society and Milken Foundation. The University of Chicago has created The Fred Andermann and Pierre Gloor Award of Excellence in Clinical Neuro-physiology to be bestowed on an individual for his or her outstanding performance in clinical neurophysiology. In 2006 he was named Officer of the Order of Canada for his work in the field of health care and in 2007 he was awarded the Peter Emil Becker Prize.
A list of recent publications can be found here http://www.mcgill.ca/neuro/
Suzanne D. DeBrosse, MD
Center for Human Genetics
University Hospitals Case Medical Center
11100 Euclid Avenue, Mailstop LKS 6055
Cleveland, OH 44106
Suzanne D. DeBrosse, M.D. is a clinical geneticist in the Center for Human Genetics at University Hospitals Case Medical Center, and a Clinical Assistant Professor of Genetics at Case Western Reserve University in Cleveland, Ohio. She is a graduate of Case Western Reserve University School of Medicine, and completed residencies in Pediatrics and Child Neurology at Rainbow Babies & Children’s Hospital. She completed her residency in Medical Genetics at University Hospitals Case Medical Center.
Dr DeBrosse is board certified in Pediatrics, Neurology with Special Qualification in Child Neurology, and Medical Genetics. She practices clinical genetics with a focus on diseases of the nervous system in children and adults.
Joshua Magleby, PhD
Integrative Neuropsychology Inc.
Consulting Psychology Inc.
3250 West Market Street, Suite 106
Fairlawn, Ohio 44333
(p) 330-873-9516, (f) 330-864-8678
Joshua Magleby, PhD is a licensed clinical neuropsychologist who focuses on the assessment and treatment of neuropsychological and psychological disorders for all age ranges. He is primarily interested in child and adolescent psychological and neuropsychological disorders, including ADHD, learning disorders, Traumatic Brain Injury, disruptive behaviors, anxiety, depression, PTSD and sleep problems. He is currently the director of Consulting Psychology/Integrative Neuropsychology, Inc., a full-time broad-based private psychology and neuropsychology practice located in Fairlawn, Ohio, with satellite offices in Canton, Kent and downtown Cleveland. He is a member of Division 40 [Neuropsychology] of the American Psychological Association, and the Ohio Psychological Association.
Dr. Magleby is a frequent lecturer on topics related to neuropsychological and psychological assessment, learning and executive function disorders, brain development, behavior management, brain-based learning, motivation, and the effects of stress and sleep deprivation on the brain. He has taught at the undergraduate and graduate levels at The University of Utah, Westminster College and Towson State University, and published research in the areas of memory and rare childhood neurodevelopmental disorders.
Dr. Magleby holds a doctorate degree in Educational Psychology from The University of Utah. He completed his predoctoral internship in Pediatric Neuropsychology and Child & Family Therapy at the Kennedy Krieger Institute/Johns Hopkins School of Medicine, after completing a 1-year school-based predoctoral internship in Utah. He then completed a 2-year residency in Clinical Neuropsychology at The Cleveland Clinic, where he specialized in Pediatric Neuropsychology but completed rotations in Adult Neuropsychology as well.
Prior to entering private practice, Dr. Magleby worked as a neuropsychologist and assessment supervisor for Applewood Centers Inc., a large community-based mental health center in downtown Cleveland. He has specialized training through experiences at LeBonheur Children’s Hospital [Memphis, TN], CBTU Autism School [Salt Lake City, UT], Neurobehavior Clinic [Salt Lake City, UT], and Stixrud & Associates [Silver Spring, MD] as well as placements in centers specializing in assessing and treating Tourette’s syndrome and Obsessive-Compulsive Disorder.
Laurie Ozelius, PhD
Associate Professor of Neurology
Harvard Medical School
Associate Neuroscientist, Neurology
Massachusetts General Hospital
16th St, Blding 114, Rm3200
Charlestown, MA 02129
Phone: 617 724-2346
Laurie Ozelius, PhD earned her Bachelor’s degree in biology from Brown University in 1984, and went on to receive a PhD in Genetics from Harvard Medical School (HMS) in 1994. She did her graduate and postdoctoral training in the lab of Xandra Breakefield, PhD, at Massachusetts General Hospital. In 1996, she joined the staff at Mass General as an instructor in neurology working in the Molecular Neurogenetics Unit under the direction of James Gusella, PhD.
In 1998, Dr. Ozelius became an Assistant Professor at HMS, and then moved to the Albert Einstein College of Medicine in New York, where she rose to the rank of Associate Professor of Molecular Genetics. In 2007 she became an Associate Professor in Genetics and Genomics Sciences and Neurology at Icahn School of Medicine at Mount Sinai in New York, where she also held the Bachmann Strauss Chair in Movement Disorders. She returned to Boston in 2015, as an Associate Professor of Neurology at HMS and an Associate Neuroscientist at Massachusetts General Hospital.
Dr. Ozelius works to uncover genetic causes for movement disorders, especially dystonias and Parkinson’s disease. In 1997, Ozelius and colleagues identified the first genetic cause for an isolated inherited dystonia, when they found mutations in the DYT1 (TOR1A) gene in patients with early onset isolated dystonia. She has also shown that variants within TOR1A are associated with the reduced penetrance of this disorder. Subsequent work uncovered two additional genes for isolated dystonia (THAP1 and GNAL), and a gene for rapid onset dystonia parkinsonism (ATP1A3).
The Ozelius laboratory also played a central role in identifying the G2019S LRRK2 gene mutation as a major cause of Parkinson’s disease in the Ashkenazi Jewish population.
Dr. Ozelius collaborates with movement disorder clinicians worldwide to collect and characterize patients and families with various inherited dystonias and other movement disorders. Her lab applies several genetic strategies, including genome-wide association studies and next-generation sequencing to identify new genes and risk factors involved in these diseases. Her work is helping to clarify the underlying mechanisms and basic pathophysiology of dystonias and PD, providing a foundation for better diagnosis and effective treatments.
Complete List of Published Work in PubMed:
Hendrik Rosewich, MD
Department of Pediatrics and Adolescent Medicine
Division of Pediatric Neurology
University Medical Center Göttingen
Georg August University
Faculty of Medicine
Office Postal Address:
D-37075 Göttingen, Germany
Phone: +49 551-39 6210
Fax: +49 551-39 6252
Dr. Rosewich, MD is an assistant Professor and Attending Physician in the Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology at the University Medical Center at Georg August University in Goettingen, Germany. His training in medicine, pediatrics and pediatric neurology has been broad at the Heinrich Heine University in Duesseldorf, Germany, in Vienna, Austria, in Zurich, Switzerland and Phoenix, AZ, USA. He did a research fellowship at the McKusick-Nathans Institute of Genetic Medicine at the Johns Hopkins University, Baltimore, MD. USA (Professor David Valle).
From the very beginning his clinical and basic research interests focused on the etiology and pathogenesis of rare neurometabolic diseases including peroxisomal disorders like Zellweger-Syndrome and X-linked Adrenoleukodytrophy as well as rare Movement Disorders like Alternating hemiplegia of childhood. Besides primary care for affected children with these disorders he is now especially interested in the investigation of the pathogenesis of Alternating hemiplegia of childhood and X-linked Adrenoleukodystrophy to answer essential questions for the development of therapeutic options.
A list of selected publications can be found here http://www.pubfacts.com/
Terence Sanger, MD, PhD
Children’s Hospital Los Angeles
4650 Sunset Blvd.
Los Angeles, CA 90027
(323) 361-2471, fax: (323) 361-1109
Terence Sanger, MD PhD, Associate Professor of Biomedical Engineering, Biokinesiology, and Child Neurology. Dr. Sanger is an Electrical Engineer and Child Neurologist specializing in movement disorders of children. His NIH funded research includes work on understanding motor learning in children, work on the use of kinematic measurements of children to design assistive communication interfaces, and multiscale modeling of large-scale neural systems for control, with particular application to understanding the development of spasticity and dystonia. He is the director of the Child Movement Disorders Clinic at Children’s Hospital of Los Angeles. His laboratory has made important recent discoveries on the role of long-latency stretch reflexes in the genesis of childhood secondary dystonia
Dr Sanger received his undergrad degree and Masters of Science both in Applied Mathematics from Harvard University. He received his MD from Harvard and went on to achieve a PhD in Electrical Engineering from MIT.
Among his many awards are:
Dystonia Medical Research Foundation Millennium award, Pfizer scholars in pediatric research award, United Cerebral Palsy Leaves of Hope award, Hume scholars award, Stanford Biodesign fellowship teaching award, American Academy of Cerebral Palsy and Developmental Medicine Goldenson award.
More information about the Sanger Lab and a list of selected publications can be found here http://sangerlab.org/index.
Masayuki Sasaki, M.D.
Chief of the Department of Child Neurology, National Center of Neurology and Psychiatry (NCNP), Japan.
After he graduated from Niigata University School of Medicine in 1983, he started clinical training for Pediatrics at Niigata University Hospital. In 1988 he started clinical training for Child Neurology at NCNP. From 1992 he studied on myelin chemistry at National Institute of Health (NIH, Bethesda, MD, USA) for 2 years. Since 1994 he has been working as a clinical child neurologist at NCNP and involved in research works on mainly neuroimaging on epilepsies, inherited metabolic disorders, and autistic spectrum disorders. He also began to study on AHC in 1999. He is an advisor doctor of Japanese AHC Family Association. A list of select publications can be found here http://www.researchgate.net/
Marcio A. Sotero de Menezes, MD
Director, Pediatric Neurology and Epilepsy
Swedish Neuroscience Institute, Pediatric Neuroscience Center and Genetic Epilepsy Clinic
Swedish Medical Center
Clinical Associate Professor, University of Washington Department of Neurology
Personal Interests: Meditation, Martial Arts and Brazilian culture
Medical School: Rio de Janeiro State University -Faculdade de Ciencias Medicas
Residency: HSE-RJ Brazil (Peds); Loyola Medical Center (Peds); Massachusetts General Hospital/Harvard Medical School (Child Neurology)
Fellowship(s): The Children’s Hospital – Boston – Harvard Medical School
Board Certifications: Board Certified in Neurology with Special Qualification in Child Neurology and Clinical Neurophysiology (ABNP)
Additional Information: Genetic Epilepies, SCN1A-mutations related epilepsy, Autossomal Dominant, Nocturnal Frontal Lobe Epilepsy, Familial Temporal Lobe Epilepsy, Familial Temporal Lobe Epilepsy with Auditory Features, (Familial Lateral Temporal Lobe Epilepsy), Familial Mesial Temporal Lobe Epilepsy, Surgical Treatment and Evaluation of Epilepsy, Vagus Nerve Stimulator Treatment for epilepsy, Skilled in intraoperative neuromonitoring.
A list of selected publications can be found here https://www.doximity.com/pub/
Sho Yano, MD., PhD
National Human Genome Research Institute
National Institutes of Health
35 Convent Drive MSC 3717, Bldg 35 Rm 1B-202
Bethesda, MD 20892
Dr Yano completed his MD at the University of Chicago Pritzker School of Medicine with a PhD in molecular genetics and cell biology studying an inhibitor of DNA replication in bacteria. He remained at the University of Chicago Comer Children’s Hospital to complete his training as a pediatric neurology fellow.
In August 2015, at the 4th ATP1A3 Symposium in Bethesda MD. Dr Yano presented an abstract and did an oral presentation on a new phenotype of the ATP1A3 mutation which has since been published. In collaboration with Dr. Silver and other physicians, he identified a group of people who have ATP1A3 mutations that cause a new syndrome, ‘fever-induced paroxysmal weakness and encephalopathy.’ These children have episodes of weakness and other neurological symptoms triggered by fevers and can take months to recover.
In the future, he hopes to pursue research to understand the molecular basis of neurological disorders as an essential step toward effective treatment.
Mary Zupanc M.D.
Medical Director of the CHOC Children’s Comprehensive Epilepsy Program and Chief of the Division of Neurology
1201 W La Veta
Orange, CA 92868
phone: (714) 509-7601
fax: (714) 509-7650
Dr. Mary Zupanc joined the PSF-CHOC-UCI faculty on February 1, 2011 as Director of the Comprehensive Epilepsy Program and Chief of the Division of Child Neurology. Dr. Zupanc is one of the country’s most highly regarded pediatric epileptologists. She received her MD degree at UCLA, her pediatric training at the University of Washington and her pediatric neurology training at the University of Wisconsin. Her training in advanced epilepsy has been broad, with additional training at the University of Wisconsin, UCLA, and Stanford University. She has been instrumental in the development of comprehensive pediatric epilepsy programs at Mayo Clinic, Columbia University, and NYU School of Medicine. Since 2001, Dr. Zupanc has been the Director of the Comprehensive Epilepsy Program and Chief of the Child Neurology Division at Children’s Hospital of Wisconsin in Milwaukee. Dr. Zupanc is boarded in Pediatrics by the American Board of Pediatrics and in Child Neurology by the American Board of Psychiatry and Neurology. She is boarded in Clinical Neurophysiology by both the American Board of Psychiatry and Neurology and the American Board of Clinical Neurophysiology.
Dr. Zupanc is highly esteemed for her scholarship and contributions to the advancement of Pediatric Neurology. She has presented at numerous nationally and internationally recognized lecture series and is a much sought after speaker.
Among Dr. Zupanc’s many awards are those for teaching recognition and clinical care at each of the major institutions she has served. She has published many articles in peer reviewed journals, most notably the Journal of Pediatric Neurology regarding pediatric epilepsy surgery and outcomes, the efficacy of Felbamate, and infantile spasms. Dr. Zupanc is the author of 15 textbook chapters including the chapter on epilepsy surgery in the primary textbook in the field: Pediatric Neurology.
Links to Dr. Zumpanc’s videos and articles can be found here: http://www.choc.org/findadoc/index.cfm?id=P00348&pid=1643