International AHC organizations are launching a new, multi-year research project led by Prof. dr. van den Maagdenberg at Leiden University Medical Centre to better understand spreading depolarization—abnormal waves of electrical activity in the brain that may drive severe and life-threatening episodes in AHC.New Jointly Funded Research Takes Aim at Brain Instability in AHC
International AHC organizations are launching a new, multi-year research project led by Prof. dr. van den Maagdenberg at Leiden University Medical Centre to better understand spreading depolarization—abnormal waves of electrical activity in the brain that may drive severe and life-threatening episodes in AHC.
This research will examine what triggers these events, how they spread through the brain, and will include early testing of medications aimed at stabilizing abnormal brain activity. This collaboration marks a decisive step toward targeted treatments, safer care, and better outcomes for individuals and families living with AHC.
As a new year begins, this work signals real momentum—bringing urgency, hope, and a clearer path forward for the AHC community. Stay engaged as this research moves forward.


